Lanmei Chen

TL;DR: A panoramic view of current exosome isolation techniques is provided, providing perspectives toward the development of novel approaches for high-efficient exosomes isolation from various types of biological matrices.

TL;DR: Antitumor mechanism studies show that Ru1 and Ru2 can cause cell cycle arrest in the G0/G1 phase by regulating cell cycle relative proteins and induce apoptosis through mitochondrial dysfunction, reactive oxygen species (ROS) accumulation and ROS-mediated DNA damage.

TL;DR: In this paper, a comprehensive overview of aptamer-based lateral flow assay (LFA) design strategies is provided to facilitate researchers to develop optimised aptamerbased LFAs, including immobilization strategies, signalling methods, and target capturing approaches.

TL;DR: Three Ru(II) complexes with salicylate as ligand were synthesized and characterized and the anticancer effect exerted by them was evaluated, found to exhibit obvious anticancer activity, in comparison with cisplatin, against cancer cell lines, while displaying low toxicity to the normal cell line BEAS-2B.

TL;DR: The results showed that ruthenium (II) methylimidazole complexes exhibited moderate antitumor activity comparable with cisplatin against A549, NCI-H460, MCF-7 and HepG2 human cancer cells, but with less toxicity to a human normal cell line HBE.