L
Lars Olson
Researcher at Karolinska Institutet
Publications - 503
Citations - 43701
Lars Olson is an academic researcher from Karolinska Institutet. The author has contributed to research in topics: Nerve growth factor & Transplantation. The author has an hindex of 108, co-authored 498 publications receiving 42512 citations. Previous affiliations of Lars Olson include Max Planck Society & St. Elizabeth Hospital.
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Ascending Monoamine Neurons to the Telencephalon and Diencephalon
TL;DR: A number of ascending monoamine neuron systems from the lower brain stem are demonstrated and mapped out by studying the anterograde and retrograde changes that occur in these neurons after various types of brain lesions.
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Protection and repair of the nigrostriatal dopaminergic system by GDNF in vivo
TL;DR: It is concluded that intracerebral GDNF administration exerts both protective and reparative effects on the nigrostriatal dopamine system, which may have implications for the development of new treatment strategies for Parkinson's disease.
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Dopamine neuron agenesis in Nurr1-deficient mice.
Rolf Zetterström,Ludmila Solomin,Ludmila Solomin,Ludmila Solomin,Lottie Jansson,Lottie Jansson,Lottie Jansson,B. Hoffer,B. Hoffer,B. Hoffer,Lars Olson,Lars Olson,Lars Olson,Thomas Perlmann,Thomas Perlmann,Thomas Perlmann +15 more
TL;DR: Results suggest that putative Nurr1 ligands may be useful for treatment of Parkinson's disease and other disorders of midbrain dopamine circuitry.
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Marrow stromal cells form guiding strands in the injured spinal cord and promote recovery
Christoph P. Hofstetter,Emily J. Schwarz,Dietmar Hess,Johan Widenfalk,A. El Manira,Darwin J. Prockop,Lars Olson +6 more
TL;DR: Marrow stromal cells constitute an easily accessible, easily expandable source of cells that may prove useful in the establishment of spinal cord repair protocols and possibly effects on functional outcome in animals rendered paraplegic.
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Brain grafts reduce motor abnormalities produced by destruction of nigrostriatal dopamine system
TL;DR: Fetal rat dopamine-containg neurons were implanted adjacent to the caudate nucleus of adult recipients whose endogenous dopaminergic input had been destroyed to suggest that such implants may be potentially useful in reversing deficits after circumscribed destruction of brain tissue.