Laura Bortolin

TL;DR: Features of brain organization are revealed, including a gene-expression module for synthesizing axonal and presynaptic components, patterns in the co-deployment of voltage-gated ion channels, functional distinctions among the cells of the vasculature and specialization of glutamatergic neurons across cortical regions.

TL;DR: An interneuron type that was previously associated with the mouse hippocampus—the ‘ivy cell’, which has neurogliaform characteristics— has become abundant across the neocortex of humans, macaques and marmosets but not mice or ferrets, and a notable subcortical innovation is found.

TL;DR: Drop-seq used to profile RNA expression in telencephalic interneurons from humans, macaques, marmosets, and mice identified an abundant striatal interneuron type in primates that had no molecularly homologous cell population in mouse striatum, cortex, thalamus, or hippocampus.

TL;DR: In this article, RNA sequencing of 79,169 single nuclei from the frontal cortex of patients and controls was performed to understand the unique molecular properties that sensitise deep-layer CSMNs to ALS.

TL;DR: An amendment to this paper has been published and can be accessed via a link at the top of the paper.