Laura J. Brylka

TL;DR: A model describing the mechanisms through which the structure, supramolecular assembly and charge distribution of collagen can control mineralization in the presence of inhibitors of hydroxyapatite nucleation is developed.

TL;DR: A combination of in situ investigations are presented, which show that for the crystallization of calcium phosphate these nanometre-sized units are in fact calcium triphosphate complexes and demonstrate how the existence of these complexes lowers the energy barrier to nucleation and unites classical and non-classical nucleation theories.

TL;DR: CryoTEM and cryoET were used to examine the CS aggregates in the hydrated state, which unambiguously confirmed the templating effect of CS/Pi in biomimetic silicification.

TL;DR: In this article , the authors show that mechanical forces associated with increased body weight at the end of adolescence, trigger the mechanoreceptor PIEZO1 and thereby mediate enhanced production of the kinase FAM20C in osteoblasts.

TL;DR: This study addressed the question, if breast cancer cells injected into immunocompromised mice would also metastasize to the spine, and if this process is influenced by the amount of trabecular bone, and found more tumor cells and clusters of different size in spine sections than in femora.