Laura Serino

TL;DR: The genome sequence of ExPEC IHE3034 (ST95) isolated from a case of neonatal meningitis is determined and the gene encoding the most protective antigen was detected in most of the E. coli isolates, highly conserved in sequence and found to be exported by a type II secretion system which seems to be nonfunctional in nonpathogenic strains.

TL;DR: The data demonstrated that outer membrane vesicles represent an ideal tool to study Gram-negative periplasm and outer membrane compartments and to shed light on new mechanisms of bacterial pathogenesis, supporting the recently proposed role of bacterial vesicle in toxin delivery to host cells.

TL;DR: It is shown that a common region exposed at the CFG face of the molecule is targeted by diverse Hi strains, however, mutation at distinct sites within this area affected the interactions of distinct strains signifying the potential for tissue tropism via this receptor.

TL;DR: It is shown that Ng‐MIP promotes the intracellular survival of N. gonorrhoeae in macrophages, highlighting a possible role of this protein in promoting the persistence of gonococcal infection.

TL;DR: The structural and functional properties of a recently reported protective antigen, named FdeC, are described and its putative role during extraintestinal pathogenic E. coli infection is elucidated by using both in vitro and in vivo infection models.