L
Laurent C. A. M. Tellier
Researcher at University of Copenhagen
Publications - 23
Citations - 11107
Laurent C. A. M. Tellier is an academic researcher from University of Copenhagen. The author has contributed to research in topics: Population & Genome. The author has an hindex of 11, co-authored 20 publications receiving 8447 citations. Previous affiliations of Laurent C. A. M. Tellier include Michigan State University.
Papers
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Journal ArticleDOI
Second-generation PLINK: rising to the challenge of larger and richer datasets
Christopher C. Chang,Carson C. Chow,Laurent C. A. M. Tellier,Shashaank Vattikuti,Shaun Purcell,James J. Lee +5 more
TL;DR: The second-generation versions of PLINK will offer dramatic improvements in performance and compatibility, and for the first time, users without access to high-end computing resources can perform several essential analyses of the feature-rich and very large genetic datasets coming into use.
Journal ArticleDOI
Second-generation PLINK: rising to the challenge of larger and richer datasets
Christopher C. Chang,Carson C. Chow,Laurent C. A. M. Tellier,Shashaank Vattikuti,Shaun Purcell,James J. Lee +5 more
TL;DR: PLINK as discussed by the authors is a C/C++ toolset for genome-wide association studies (GWAS) and research in population genetics, which has been widely used in the literature.
Journal ArticleDOI
Accurate Genomic Prediction of Human Height
Louis Lello,Steven G. Avery,Laurent C. A. M. Tellier,Laurent C. A. M. Tellier,Ana I. Vazquez,Gustavo de los Campos,Stephen D. H. Hsu +6 more
TL;DR: The authors constructed genomic predictors for heritable but extremely complex human quantitative traits (height, heel bone density, and educational attainment) using modern methods in high dimensional statistics (i.e., machine learning).
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De novo assembly of a haplotype-resolved human genome
Hongzhi Cao,Honglong Wu,Ruibang Luo,Shujia Huang,Yuhui Sun,Xin Tong,Yinlong Xie,Binghang Liu,Hailong Yang,Hancheng Zheng,Jian Li,Bo Li,Yu Wang,Fang Yang,Peng Sun,Siyang Liu,Peng Gao,Haodong Huang,Sun Jing,Dan Chen,Guangzhu He,Weihua Huang,Zheng Huang,Li Yue,Laurent C. A. M. Tellier,Xiao Liu,Qiang Feng,Xun Xu,Xiuqing Zhang,Lars Bolund,Anders Krogh,Karsten Kristiansen,Radoje Drmanac,Snezana Drmanac,Rasmus Nielsen,Songgang Li,Jian Wang,Huanming Yang,Yingrui Li,Gane Ka-Shu Wong,Jun Wang +40 more
TL;DR: This haplotype-resolved diploid genome represents the most complete de novo human genome assembly to date and should aid in translating genotypes to phenotypes for the development of personalized medicine.
Journal ArticleDOI
Genomic Prediction of 16 Complex Disease Risks Including Heart Attack, Diabetes, Breast and Prostate Cancer
TL;DR: Risk predictors using polygenic scores computed from common Single Nucleotide Polymorphisms (SNPs) for a number of complex disease conditions, using L1-penalized regression on case-control data from UK Biobank are constructed.