F
Fang Yang
Publications - 4
Citations - 138
Fang Yang is an academic researcher. The author has contributed to research in topics: Clopidogrel & Percutaneous coronary intervention. The author has an hindex of 2, co-authored 4 publications receiving 117 citations.
Papers
More filters
Journal ArticleDOI
De novo assembly of a haplotype-resolved human genome
Hongzhi Cao,Honglong Wu,Ruibang Luo,Shujia Huang,Yuhui Sun,Xin Tong,Yinlong Xie,Binghang Liu,Hailong Yang,Hancheng Zheng,Jian Li,Bo Li,Yu Wang,Fang Yang,Peng Sun,Siyang Liu,Peng Gao,Haodong Huang,Sun Jing,Dan Chen,Guangzhu He,Weihua Huang,Zheng Huang,Li Yue,Laurent C. A. M. Tellier,Xiao Liu,Qiang Feng,Xun Xu,Xiuqing Zhang,Lars Bolund,Anders Krogh,Karsten Kristiansen,Radoje Drmanac,Snezana Drmanac,Rasmus Nielsen,Songgang Li,Jian Wang,Huanming Yang,Yingrui Li,Gane Ka-Shu Wong,Jun Wang +40 more
TL;DR: This haplotype-resolved diploid genome represents the most complete de novo human genome assembly to date and should aid in translating genotypes to phenotypes for the development of personalized medicine.
Journal ArticleDOI
An integrated tool to study MHC region: accurate SNV detection and HLA genes typing in human MHC region using targeted high-throughput sequencing.
Hongzhi Cao,Jinghua Wu,Yu Wang,Hui Jiang,Tao Zhang,Xiao Liu,Yinyin Xu,Dequan Liang,Peng Gao,Yepeng Sun,Benjamin Gifford,Mark D'Ascenzo,Xiaomin Liu,Laurent C. A. M. Tellier,Fang Yang,Xin Tong,Dan Chen,Jing Zheng,Weiyang Li,Todd Richmond,Xun Xu,Jun Wang,Yingrui Li +22 more
TL;DR: A cost-effective and highly accurate approach for variant detection and HLA typing in the MHC region is presented, which may lend further insight into immune-mediated diseases studies, and may find clinical utility in transplantation medicine research.
Journal ArticleDOI
New genetic variants associated with major adverse cardiovascular events in patients with acute coronary syndromes and treated with clopidogrel and aspirin.
Xiaomin Liu,Hanshi Xu,Xu Huaiqian,Qingshan Geng,Qingshan Geng,Wai-Ho Mak,Fei Ling,Zheng Su,Fang Yang,Tao Zhang,Jiyan Chen,Jiyan Chen,Huanming Yang,Jian Wang,Xiuqing Zhang,Xun Xu,Huijue Jia,Zhiwei Zhang,Zhiwei Zhang,Xiao Liu,Shilong Zhong,Shilong Zhong +21 more
TL;DR: Wang et al. as mentioned in this paper identified new genetic variants associated with major adverse cardiovascular events (MACE) in patients with acute coronary syndromes and those undergoing percutaneous coronary intervention (PCI) during the 18-month follow-up period by a two-stage large-scale sequencing data, including high-depth whole exome sequencing of 168 patients in the discovery cohort.
Posted ContentDOI
New genetic variants associated with major adverse cardiovascular events in patients with acute coronary syndromes and treated with clopidogrel and aspirin
Xiaomin Liu,Hanshi Xu,Xu Huaiqian,Qingshan Geng,Wai-Ho Mak,Fei Ling,Zheng Su,Fang Yang,Tao Zhang,Jiyan Chen,Huanming Yang,Jian Wang,Xiuqing Zhang,Xun Xu,Huijue Jia,Zhiwei Zhang,Xiao Liu,Shilong Zhong +17 more
TL;DR: Six new genotypes associated with MACE are discovered and confirmed and the first superior classifier for predicting MACE is developed, which may help clinician to make decision on the therapeutic intervention for ACS patients.