L
Lawrence M. Title
Researcher at Dalhousie University
Publications - 42
Citations - 7329
Lawrence M. Title is an academic researcher from Dalhousie University. The author has contributed to research in topics: Coronary artery disease & Myocardial infarction. The author has an hindex of 25, co-authored 39 publications receiving 6910 citations. Previous affiliations of Lawrence M. Title include Halifax & Montreal Heart Institute.
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Journal ArticleDOI
Optimal Medical Therapy with or without PCI for Stable Coronary Disease
William E. Boden,Koon K. Teo,Pamela M. Hartigan,David J. Maron,William J. Kostuk,Merril L. Knudtson,Marcin Dada,Paul Casperson,Crystal L. Harris,Bernard R. Chaitman,Leslee J. Shaw,Gilbert Gosselin,Shah Nawaz,Lawrence M. Title,Gerald T. Gau,Alvin Blaustein,David C. Booth,Eric R. Bates,John A. Spertus,Daniel S. Berman,William S. Weintraub +20 more
TL;DR: As an initial management strategy in patients with stable coronary artery disease, PCI did not reduce the risk of death, myocardial infarction, or other major cardiovascular events when added to optimal medical therapy.
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The Canadian study of the sirolimus-eluting stent in the treatment of patients with long de novo lesions in small native coronary arteries (C-SIRIUS)
Erick Schampaert,Eric A. Cohen,Michael Schlüter,François Reeves,Mouhieddin Traboulsi,Lawrence M. Title,Richard E. Kuntz,Jeffrey J. Popma +7 more
TL;DR: In patients with long lesions in small vessels, the SES dramatically reduces the risk of restenosis at eight months, translating into an excellent clinical outcome at nine months.
Journal ArticleDOI
Microvascular Function Predicts Cardiovascular Events in Primary Prevention Long-Term Results From the Firefighters and Their Endothelium (FATE) Study
Todd J. Anderson,Francois Charbonneau,Lawrence M. Title,Jean Buithieu,M. Sarah Rose,Heather Conradson,Kathy Hildebrand,Marinda Fung,Subodh Verma,Eva Lonn +9 more
TL;DR: Hyperemic velocity, a newly described marker of microvascular function, is a novel tool that may improve risk stratification of lower-risk healthy men and was a significant risk marker for adverse cardiovascular outcomes.
Journal ArticleDOI
Oral glucose loading acutely attenuates endothelium-dependent vasodilation in healthy adults without diabetes: an effect prevented by vitamins C and E.
TL;DR: Oral glucose loading causes an acute, transient decrease of endothelium-dependent flow-mediated dilation of the brachial artery in healthy subjects without diabetes, which is prevented by vitamins C and E, indicating that vitamins prevented the glucose-induced attenuation of FMD.
Journal ArticleDOI
Effects of the Acyl Coenzyme A:Cholesterol Acyltransferase Inhibitor Avasimibe on Human Atherosclerotic Lesions
Jean-Claude Tardif,Jean Grégoire,Philippe L. L’Allier,Todd J. Anderson,Olivier F. Bertrand,François Reeves,Lawrence M. Title,Fernando Alfonso,Erick Schampaert,Alita Hassan,Richard McLain,Milton L. Pressler,Reda Ibrahim,Jacques Lespérance,John Blue,Therese Heinonen,Josep Rodés-Cabau +16 more
TL;DR: Avasimibe did not favorably alter coronary atherosclerosis as assessed by IVUS, and this ACAT inhibitor also caused a mild increase in LDL cholesterol.