L
Lennart Pedersen
Publications - 7
Citations - 782
Lennart Pedersen is an academic researcher. The author has contributed to research in topics: Autism & Cronbach's alpha. The author has an hindex of 6, co-authored 6 publications receiving 763 citations.
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Journal ArticleDOI
A genomewide screen for autism: strong evidence for linkage to chromosomes 2q, 7q and 16p
Le, Couteur, A,Thomas Kelly,T Berney,Helen McConachie,Jeremy R. Parr,Sarah Palferman,Nicola Matthews,Martha Turner,Janette Moore,Amaia Hervas,Anne Aubin,Simon Wallace,Janine Michelotti,Catherine Wainhouse,Alina Paul,Emily J. Thompson,Ramyani Gupta,Claire Garner,Marianne Murin,Christine M. Freitag,Nuala Ryder,E Cottington,Andrew Pickles,Michael Rutter,Anthony J. Bailey,Gabrielle Barnby,Janine A. Lamb,Angela J. Marlow,Pat Scudder,Anthony P. Monaco,Gillian Baird,Antony Cox,Zoe Docherty,Pamela Warburton,Elizabeth P. Green,Stephen Abbs,De, Vries, Pj,Patrick Bolton,Jonathan Green,Anne Gilchrist,Jane Whittacker,Bryan Bolton,Ros Packer,Elena Maestrini,Francesca Blasi,Van, Engeland, H,De, Jonge, Mv,Chantal Kemner,Sabine M. Klauck,Kim S. Beyer,Sabine Epp,Annemarie Poustka,Axel Benner,JW Goethe,Fritz Poustka,Dorothea Rühl,Gabriele Schmötzer,S Boolte,Sabine Feineis-Matthews,Eric Fombonne,B Rogee,Jeanne Fremolle-Kruck,Catherine Pienkowski,Maïté Tauber,Lennart Pedersen,KB Nielsen,Gunna Eriksen,Demetrious Haracopos,Rmj Cotterill,John Tsiantis,Katerina Papanikolaou,Catherine Lord,Christina Corsello,Stephen J. Guter,Bennett L. Leventhal,Edwin H. Cook,Susan L. Smalley,Julia Bailey,James J. McGough,Jennifer G. Levitt,David Pauls,Fred R. Volkmar,Daniel E. Weeks,Int, Mol, Genetic, Study, Autism, Cons +83 more
TL;DR: The addition of new families and markers provides further support for previous reports of linkages on chromosomes 7q and 16p and two new regions of linkage have also been identified on chromosomes 2q and 17q.
Journal ArticleDOI
Further characterization of the autism susceptibility locus AUTS1 on chromosome 7q
Sarah Palferman,Nicola Matthews,Martha Turner,Janette Moore,Amaia Hervas,Anne Aubin,Simon Wallace,Janine Michelotti,Catherine Wainhouse,Alina Paul,Elaine Thompson,Marianne Murin,Ramyani Gupta,Claire Garner,Andrew Pickles,Michael Rutter,Anthony J. Bailey,Anthony J. Bailey,Janine A. Lamb,Angela J. Marlow,Pat Scudder,Gabrielle Barnby,Anthony P. Monaco,Gillian Baird,Anthony Cox,Zoe Docherty,Pamela Warburton,Elizabeth P. Green,Stephen Abbs,Ann Le Couteur,Helen McConachie,Tom Berney,Thomas Kelly,Petrus J. de Vries,Patrick Bolton,Jonathan Green,Anne Gilchrist,Jane Whittacker,Bryan Bolton,Ros Packer,Elena Maestrini,Herman van Engeland,Maretha de Jonge,Chantal Kemner,Sabine M. Klauck,Kim S. Beyer,Sabine Epp,Annemarie Poustka,Axel Benner,Fritz Poustka,Dorothea Rühl,Gabriele Schmötzer,Sven Bölte,Sabine Feineis-Matthews,Eric Fombonne,Bernadette Rogé,Jeanne Fremolle-Kruck,Catherine Pienkowski,Marie Thérèse Tauber,Lennart Pedersen,Karen Brøndum-Nielsen,Gunna Eriksen,Demetrious Haracopos,Rodney M. J. Cotterill,John Tsiantis,Katerina Papanikolaou,Catherine Lord,Christina Corsello,Stephen J. Guter,Bennett L. Leventhal,Edwin H. Cook,Susan L. Smalley,Julia Bailey,Amy Liu,Martha Dedricks,Lisa Chrzanowski,Jennifer G. Levitt,David L. Pauls,Fred R. Volkmar,Daniel E. Weeks +79 more
TL;DR: The most significant susceptibility region in the first whole genome screen of multiplex families was on chromosome 7q, although this linkage was evident only in UK IMGSAC families.
Journal ArticleDOI
Mutation screening and association analysis of six candidate genes for autism on chromosome 7q
Elena Bonora,Janine A. Lamb,Gabrielle Barnby,Nuala Sykes,Thomas Moberly,Kim S. Beyer,Sabine M. Klauck,Firtz Poustka,Elena Bacchelli,Francesca Blasi,Elena Maestrini,Agatino Battaglia,Demetrios Haracopos,Lennart Pedersen,Torben Isager,Gunna Eriksen,Birgitte Viskum,Ester Ulsted Sorensen,Karen Brøndum-Nielsen,Rodney M. J. Cotterill,Herman von Engeland,Maretha de Jonge,Chantal Kemner,Karlijn Steggehuis,Margret Scherpenisse,Michael Rutter,Patrick Bolton,Jeremy R. Parr,Annemarie Poustka,Anthony J. Bailey,Anthony P. Monaco +30 more
TL;DR: Analysis of genetic variants provided evidence for association with autism for one of the new missense changes identified in LAMB1; this effect was stronger in a subgroup of affected male sibling pair families, implying a possible specific sex-related effect for this variant.
Further characterization of the autism susceptibility locus AUTS1 on chromosome 7q International Molecular Genetic Study of Autism Consortium (IMGSAC)
Sarah Palferman,Nicola Matthews,Martha Turner,Janette Moore,Amaia Hervas,Anne Aubin,Simon Wallace,Janine Michelotti,Catherine Wainhouse,Alina Paul,Elaine Thompson,Marianne Murin,Ramyani Gupta,Claire Garner,Andrew Pickles,Michael Rutter,Anthony J. Bailey,Janine A. Lamb,Angela J. Marlow,Pat Scudder,Gabrielle Barnby,Anthony P. Monaco,Gillian Baird,Anthony Cox,Zoe Docherty,Pamela Warburton,Elizabeth P. Green,Stephen Abbs,Helen McConachie,Tom Berney,Thomas Kelly,Petrus J. de Vries,Patrick Bolton,Jonathan Green,Anne Gilchrist,Jane Whittacker,Bryan Bolton,Ros Packer,Herman van Engeland,Maretha de Jonge,Sabine M. Klauck,Kim S. Beyer,Sabine Epp,Annemarie Poustka,Axel Benner,Fritz Poustka,Dorothea Rühl,Eric Fombonne,Jeanne Fremolle-Kruck,Catherine Pienkowski,Marie-Thérèse Tauber,Lennart Pedersen,Gunna Eriksen,John Tsiantis,Katerina Papanikolaou,Catherine Lord,Christina Corsello,Stephen J. Guter,Bennett L. Leventhal,Susan L. Smalley,Julia Bailey,Amy Liu,Martha Dedricks,Lisa Chrzanowski,Jennifer G. Levitt,David Pauls,Fred Volkmar +66 more
TL;DR: Linkage disequilibrium mapping identified two regions of association-one lying under the peak of linkage, the other some 27 cM distal, supported in part by findings in independent German and American singleton families.
Journal ArticleDOI
New Interview and Observation Measures of the Broader Autism Phenotype : Description of Strategy and Reliability Findings for the Interview Measures
Jeremy R. Parr,Jeremy R. Parr,Maretha de Jonge,Simon Wallace,Andrew Pickles,Michael Rutter,Ann Le Couteur,Herman van Engeland,Kerstin Wittemeyer,Helen McConachie,Bernadette Rogé,Carine Mantoulan,Lennart Pedersen,Torben Isager,Fritz Poustka,Sven Bölte,Sven Bölte,Patrick Bolton,Emma Weisblatt,Jonathan Green,Katerina Papanikolaou,Gillian Baird,Anthony J. Bailey,Anthony J. Bailey +23 more
TL;DR: Two interview measures showed good reliability and substantial stability over time, but the findings were better for factor 1 than factor 2, and it is recommended factor 1 scores be used for characterising the BAP.