J
Jeremy R. Parr
Researcher at Newcastle University
Publications - 144
Citations - 20182
Jeremy R. Parr is an academic researcher from Newcastle University. The author has contributed to research in topics: Autism & Autism spectrum disorder. The author has an hindex of 45, co-authored 126 publications receiving 17066 citations. Previous affiliations of Jeremy R. Parr include Boston Children's Hospital & University of Oxford.
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Journal ArticleDOI
Synaptic, transcriptional and chromatin genes disrupted in autism
Silvia De Rubeis,Xin-Xin He,Arthur P. Goldberg,Christopher S. Poultney,Kaitlin E. Samocha,A. Ercument Cicek,Yan Kou,Li Liu,Menachem Fromer,Menachem Fromer,R. Susan Walker,Tarjinder Singh,Lambertus Klei,Jack A. Kosmicki,Shih-Chen Fu,Branko Aleksic,Monica Biscaldi,Patrick Bolton,Jessica M. Brownfeld,Jinlu Cai,Nicholas G. Campbell,Angel Carracedo,Angel Carracedo,Maria H. Chahrour,Andreas G. Chiocchetti,Hilary Coon,Emily L. Crawford,Lucy Crooks,Sarah Curran,Geraldine Dawson,Eftichia Duketis,Bridget A. Fernandez,Louise Gallagher,Evan T. Geller,Stephen J. Guter,R. Sean Hill,R. Sean Hill,Iuliana Ionita-Laza,Patricia Jiménez González,Helena Kilpinen,Sabine M. Klauck,Alexander Kolevzon,Irene Lee,Jing Lei,Terho Lehtimäki,Chiao-Feng Lin,Avi Ma'ayan,Christian R. Marshall,Alison L. McInnes,Benjamin M. Neale,Michael John Owen,Norio Ozaki,Mara Parellada,Jeremy R. Parr,Shaun Purcell,Kaija Puura,Deepthi Rajagopalan,Karola Rehnström,Abraham Reichenberg,Aniko Sabo,Michael Sachse,Stephen Sanders,Chad M. Schafer,Martin Schulte-Rüther,David Skuse,David Skuse,Christine Stevens,Peter Szatmari,Kristiina Tammimies,Otto Valladares,Annette Voran,Li-San Wang,Lauren A. Weiss,A. Jeremy Willsey,Timothy W. Yu,Timothy W. Yu,Ryan K. C. Yuen,Edwin H. Cook,Christine M. Freitag,Michael Gill,Christina M. Hultman,Thomas Lehner,Aarno Palotie,Aarno Palotie,Aarno Palotie,Gerard D. Schellenberg,Pamela Sklar,Matthew W. State,James S. Sutcliffe,Christopher A. Walsh,Christopher A. Walsh,Stephen W. Scherer,Michael E. Zwick,Jeffrey C. Barrett,David J. Cutler,Kathryn Roeder,Bernie Devlin,Mark J. Daly,Mark J. Daly,Joseph D. Buxbaum +99 more
TL;DR: Using exome sequencing, it is shown that analysis of rare coding variation in 3,871 autism cases and 9,937 ancestry-matched or parental controls implicates 22 autosomal genes at a false discovery rate of < 0.05, plus a set of 107 genes strongly enriched for those likely to affect risk (FDR < 0.30).
Journal ArticleDOI
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs
S. Hong Lee,Stephan Ripke,Stephan Ripke,Benjamin M. Neale,Benjamin M. Neale,Stephen V. Faraone,Shaun Purcell,Shaun Purcell,Shaun Purcell,Roy H. Perlis,Roy H. Perlis,Bryan J. Mowry,Bryan J. Mowry,Anita Thapar,Michael E. Goddard,John S. Witte,Devin Absher,Ingrid Agartz,Huda Akil,Farooq Amin,Ole A. Andreassen,Adebayo Anjorin,Richard Anney,Verneri Anttila,Dan E. Arking,Philip Asherson,Maria Helena Pinto de Azevedo,Lena Backlund,Judith A. Badner,Anthony J. Bailey,Tobias Banaschewski,Jack D. Barchas,Michael R. Barnes,Thomas B. Barrett,Nicholas Bass,Agatino Battaglia,Michael Bauer,Mònica Bayés,Frank Bellivier,Sarah E. Bergen,Sarah E. Bergen,Sarah E. Bergen,Wade H. Berrettini,Catalina Betancur,Catalina Betancur,Catalina Betancur,Thomas Bettecken,Joseph Biederman,Elisabeth B. Binder,Donald W. Black,Douglas Blackwood,Cinnamon S. Bloss,Michael Boehnke,Dorret I. Boomsma,Gerome Breen,Gerome Breen,René Breuer,Richard Bruggeman,Paul Cormican,Nancy G. Buccola,Jan K. Buitelaar,William E. Bunney,Joseph D. Buxbaum,William Byerley,Enda M. Byrne,Sian Caesar,Wiepke Cahn,Rita M. Cantor,Miguel Casas,Aravinda Chakravarti,Kimberly Chambert,Khalid Choudhury,Sven Cichon,Sven Cichon,C. Robert Cloninger,David A. Collier,Edwin H. Cook,Hilary Coon,Bru Cormand,Aiden Corvin,William Coryell,David Craig,Ian W. Craig,Jennifer Crosbie,Michael L. Cuccaro,David Curtis,Darina Czamara,Susmita Datta,Geraldine Dawson,Richard O. Day,Eco J. C. de Geus,Franziska Degenhardt,Srdjan Djurovic,Gary Donohoe,Alysa E. Doyle,Jubao Duan,Frank Dudbridge,Eftichia Duketis,Richard P. Ebstein,Howard J. Edenberg,Josephine Elia,Sean Ennis,Bruno Etain,Ayman H. Fanous,Ayman H. Fanous,Anne Farmer,I. Nicol Ferrier,Matthew Flickinger,Eric Fombonne,Tatiana Foroud,Josef Frank,Barbara Franke,Christine Fraser,Robert Freedman,Nelson B. Freimer,Christine M. Freitag,Marion Friedl,Louise Frisén,Louise Gallagher,Pablo V. Gejman,Lyudmila Georgieva,Elliot S. Gershon,Daniel H. Geschwind,Ina Giegling,Michael Gill,Scott D. Gordon,Katherine Gordon-Smith,Katherine Gordon-Smith,Elaine K. Green,Tiffany A. Greenwood,Dorothy E. Grice,Magdalena Gross,Detelina Grozeva,Weihua Guan,Weihua Guan,Hugh Gurling,Lieuwe de Haan,Jonathan L. Haines,Hakon Hakonarson,Joachim Hallmayer,Steven P. Hamilton,Marian L. Hamshere,Thomas Hansen,Annette M. Hartmann,Martin Hautzinger,Andrew C. Heath,Anjali K. Henders,Stefan Herms,Stefan Herms,Ian B. Hickie,Maria Hipolito,Susanne Hoefels,Peter Holmans,Florian Holsboer,Witte J.G. Hoogendijk,Jouke-Jan Hottenga,Christina M. Hultman,Vanessa Hus,Andres Ingason,Marcus Ising,Stéphane Jamain,Edward G. Jones,Ian Jones,Lisa Jones,Jung-Ying Tzeng,Anna K. Kähler,René S. Kahn,Radhika Kandaswamy,Matthew C. Keller,James L. Kennedy,Elaine Kenny,Lindsey Kent,Yunjung Kim,George Kirov,Sabine M. Klauck,Lambertus Klei,James A. Knowles,Martin A. Kohli,Daniel L. Koller,Bettina Konte,Ania Korszun,Lydia Krabbendam,Robert Krasucki,Jonna Kuntsi,Phoenix Kwan,Mikael Landén,Mikael Landén,Niklas Långström,Mark Lathrop,Jacob Lawrence,William Lawson,Marion Leboyer,David H. Ledbetter,Phil Lee,Todd Lencz,Todd Lencz,Klaus-Peter Lesch,Klaus-Peter Lesch,Douglas F. Levinson,Cathryn M. Lewis,Jun Li,Paul Lichtenstein,Jeffrey A. Lieberman,Danyu Lin,Don H. Linszen,Chunyu Liu,Falk W. Lohoff,Sandra K. Loo,Catherine Lord,Jennifer K. Lowe,Susanne Lucae,Donald J. MacIntyre,Pamela A. F. Madden,Elena Maestrini,Patrik K. E. Magnusson,Pamela B. Mahon,Wolfgang Maier,Anil K. Malhotra,Anil K. Malhotra,Shrikant Mane,Christa Lese Martin,Nicholas G. Martin,Manuel Mattheisen,Manuel Mattheisen,Keith Matthews,Morten Mattingsdal,Steven A. McCarroll,Kevin A. McGhee,James J. McGough,Patrick J. McGrath,Peter McGuffin,Melvin G. McInnis,Andrew M. McIntosh,Rebecca McKinney,Alan W. McLean,Francis J. McMahon,William M. McMahon,Andrew McQuillin,Helena Medeiros,Sarah E. Medland,Sandra Meier,Ingrid Melle,Fan Meng,Jobst Meyer,Christel M. Middeldorp,Lefkos T. Middleton,Vihra Milanova,Ana Miranda,Anthony P. Monaco,Anthony P. Monaco,Grant W. Montgomery,Jennifer L. Moran,Daniel Moreno-De-Luca,Gunnar Morken,Derek W. Morris,Eric M. Morrow,Valentina Moskvina,Pierandrea Muglia,Thomas W. Mühleisen,Walter J. Muir,Bertram Müller-Myhsok,Michael T. Murtha,Richard M. Myers,Inez Myin-Germeys,Michael C. Neale,Stan F. Nelson,Caroline M. Nievergelt,Ivan Nikolov,Vishwajit L. Nimgaonkar,Willem A. Nolen,Markus M. Nöthen,John I. Nurnberger,Evaristus A. Nwulia,Dale R. Nyholt,Colm O'Dushlaine,Robert D. Oades,Ann Olincy,Guiomar Oliveira,Line Olsen,Roel A. Ophoff,Roel A. Ophoff,Urban Ösby,Michael John Owen,Aarno Palotie,Jeremy R. Parr,Andrew D. Paterson,Carlos N. Pato,Michele T. Pato,Brenda W.J.H. Penninx,Michele L. Pergadia,Margaret A. Pericak-Vance,Benjamin S. Pickard,Jonathan Pimm,Joseph Piven,Danielle Posthuma,Danielle Posthuma,James B. Potash,Fritz Poustka,Peter Propping,Vinay Puri,Digby Quested,Emma M. Quinn,Josep Antoni Ramos-Quiroga,Henrik B. Rasmussen,Soumya Raychaudhuri,Soumya Raychaudhuri,Karola Rehnström,Andreas Reif,Marta Ribasés,John P. Rice,Marcella Rietschel,Kathryn Roeder,Herbert Roeyers,Lizzy Rossin,Aribert Rothenberger,Guy A. Rouleau,Douglas M. Ruderfer,Dan Rujescu,Alan R. Sanders,Stephen Sanders,Susan L. Santangelo,Susan L. Santangelo,Joseph A. Sergeant,Russell Schachar,Martin Schalling,Alan F. Schatzberg,William A. Scheftner,Gerard D. Schellenberg,Stephen W. Scherer,Nicholas J. Schork,Thomas G. Schulze,Thomas G. Schulze,Johannes Schumacher,Markus J. Schwarz,Edward M. Scolnick,Laura J. Scott,Jianxin Shi,Paul D. Shilling,Stanley I. Shyn,Jeremy M. Silverman,Susan L. Slager,Susan L. Smalley,Johannes H. Smit,Erin N. Smith,Edmund J.S. Sonuga-Barke,Edmund J.S. Sonuga-Barke,David St Clair,Matthew W. State,Michael Steffens,Hans-Christoph Steinhausen,Hans-Christoph Steinhausen,Hans-Christoph Steinhausen,John Strauss,Jana Strohmaier,T. Scott Stroup,James S. Sutcliffe,Peter Szatmari,Szabocls Szelinger,Srinivasa Thirumalai,Robert C. Thompson,Alexandre A. Todorov,Federica Tozzi,Jens Treutlein,Manfred Uhr,Edwin J. C. G. van den Oord,Gerard van Grootheest,Jim van Os,Astrid M. Vicente,Astrid M. Vicente,Astrid M. Vicente,Veronica J. Vieland,John B. Vincent,Peter M. Visscher,Christopher A. Walsh,Thomas H. Wassink,Stanley J. Watson,Myrna M. Weissman,Thomas Werge,Thomas F. Wienker,Ellen M. Wijsman,Gonneke Willemsen,Nigel Williams,A. Jeremy Willsey,Stephanie H. Witt,Wei Xu,Allan H. Young,Allan H. Young,Timothy W. Yu,Stanley Zammit,Peter P. Zandi,Peng Zhang,Frans G. Zitman,Sebastian Zöllner,Bernie Devlin,John R. Kelsoe,John R. Kelsoe,Pamela Sklar,Mark J. Daly,Mark J. Daly,Michael Conlon O'Donovan,Nicholas John Craddock,Patrick F. Sullivan,Jordan W. Smoller,Jordan W. Smoller,Kenneth S. Kendler,Naomi R. Wray +405 more
TL;DR: Empirical evidence of shared genetic etiology for psychiatric disorders can inform nosology and encourages the investigation of common pathophysiologies for related disorders.
Journal ArticleDOI
Functional impact of global rare copy number variation in autism spectrum disorders
Dalila Pinto,Alistair T. Pagnamenta,Lambertus Klei,Richard Anney,Daniele Merico,Regina Regan,Judith Conroy,Tiago R. Magalhaes,Tiago R. Magalhaes,Catarina Correia,Catarina Correia,Brett S. Abrahams,Joana Almeida,Elena Bacchelli,Gary D. Bader,Anthony J. Bailey,Gillian Baird,Agatino Battaglia,Tom Berney,Nadia Bolshakova,Sven Bölte,Patrick Bolton,Thomas Bourgeron,Sean Brennan,Jessica Brian,Susan E. Bryson,Andrew R. Carson,Guillermo Casallo,Jillian P. Casey,Brian H.Y. Chung,Lynne E Cochrane,Christina Corsello,Emily L. Crawford,Andrew Crossett,Cheryl Cytrynbaum,Geraldine Dawson,Maretha de Jonge,Richard Delorme,Irene Drmic,Eftichia Duketis,Frederico Duque,Annette Estes,Penny Farrar,Bridget A. Fernandez,Susan E. Folstein,Eric Fombonne,Christine M. Freitag,John Gilbert,Christopher Gillberg,Joseph T. Glessner,Jeremy Goldberg,Andrew Green,Jonathan Green,Stephen J. Guter,Hakon Hakonarson,Elizabeth A. Heron,Matthew Hill,Richard Holt,Jennifer L. Howe,Gillian Hughes,Vanessa Hus,Roberta Igliozzi,Cecilia Kim,Sabine M. Klauck,Alexander Kolevzon,Olena Korvatska,Vlad Kustanovich,Clara Lajonchere,Janine A. Lamb,Magdalena Laskawiec,Marion Leboyer,Ann Le Couteur,Bennett L. Leventhal,Anath C. Lionel,Anath C. Lionel,Xiao-Qing Liu,Catherine Lord,Linda Lotspeich,Sabata C. Lund,Elena Maestrini,William M. Mahoney,Carine Mantoulan,Christian R. Marshall,Helen McConachie,Christopher J. McDougle,Jane McGrath,William M. McMahon,Alison K. Merikangas,Ohsuke Migita,Nancy J. Minshew,Ghazala Mirza,Jeff Munson,Stanley F. Nelson,Carolyn Noakes,Abdul Noor,Gudrun Nygren,Guiomar Oliveira,Katerina Papanikolaou,Jeremy R. Parr,Barbara Parrini,Tara Paton,Andrew Pickles,Marion Pilorge,Joseph Piven,Chris P. Ponting,David J. Posey,Annemarie Poustka,Fritz Poustka,Aparna Prasad,Jiannis Ragoussis,Katy Renshaw,Jessica Rickaby,Wendy Roberts,Kathryn Roeder,Bernadette Rogé,Michael Rutter,Laura J. Bierut,John P. Rice,Jeff Salt,Katherine Sansom,Daisuke Sato,Ricardo Segurado,Ana Filipa Sequeira,Lili Senman,Lili Senman,Naisha Shah,Val C. Sheffield,Latha Soorya,Inês Sousa,Olaf Stein,Nuala Sykes,Vera Stoppioni,Christina Strawbridge,Raffaella Tancredi,Katherine E. Tansey,Bhooma Thiruvahindrapduram,Ann P. Thompson,Susanne Thomson,Ana Tryfon,John Tsiantis,Herman Van Engeland,John B. Vincent,Fred R. Volkmar,Simon Wallace,Kai Wang,Zhouzhi Wang,Thomas H. Wassink,Caleb Webber,Rosanna Weksberg,Kirsty Wing,Kerstin Wittemeyer,Shawn Wood,Jing Wu,Brian L. Yaspan,Danielle Zurawiecki,Lonnie Zwaigenbaum,Joseph D. Buxbaum,Rita M. Cantor,Edwin H. Cook,Hilary Coon,Michael L. Cuccaro,Bernie Devlin,Sean Ennis,Louise Gallagher,Daniel H. Geschwind,Michael Gill,Jonathan L. Haines,Joachim Hallmayer,Judith Miller,Anthony P. Monaco,John I. Nurnberger,Andrew D. Paterson,Margaret A. Pericak-Vance,Gerard D. Schellenberg,Peter Szatmari,Astrid M. Vicente,Veronica J. Vieland,Veronica J. Vieland,Ellen M. Wijsman,Stephen W. Scherer,James S. Sutcliffe,Catalina Betancur +181 more
TL;DR: The genome-wide characteristics of rare (<1% frequency) copy number variation in ASD are analysed using dense genotyping arrays to reveal many new genetic and functional targets in ASD that may lead to final connected pathways.
Journal ArticleDOI
Analysis of shared heritability in common disorders of the brain
Verneri Anttila,Verneri Anttila,Brendan Bulik-Sullivan,Brendan Bulik-Sullivan,Hilary K. Finucane,Raymond K. Walters,Raymond K. Walters,Jose Bras,Laramie E. Duncan,Valentina Escott-Price,Guido J. Falcone,Padhraig Gormley,Rainer Malik,Nikolaos A. Patsopoulos,Nikolaos A. Patsopoulos,Stephan Ripke,Zhi Wei,Dongmei Yu,Dongmei Yu,Phil Lee,Phil Lee,Patrick Turley,Patrick Turley,Benjamin Grenier-Boley,Benjamin Grenier-Boley,Benjamin Grenier-Boley,Vincent Chouraki,Yoichiro Kamatani,Claudine Berr,Claudine Berr,Luc Letenneur,Luc Letenneur,Didier Hannequin,Philippe Amouyel,Anne Boland,Jean-François Deleuze,Emmanuelle Duron,Badri N. Vardarajan,Christiane Reitz,Alison Goate,Matthew J. Huentelman,M. Ilyas Kamboh,Eric B. Larson,Eric B. Larson,Ekaterina Rogaeva,Peter St George-Hyslop,Peter St George-Hyslop,Hakon Hakonarson,Walter A. Kukull,Lindsay A. Farrer,Lisa L. Barnes,Thomas G. Beach,F. Yesim Demirci,Elizabeth Head,Christine M. Hulette,Gregory A. Jicha,John S. K. Kauwe,Jeffrey Kaye,James B. Leverenz,Allan I. Levey,Andrew P. Lieberman,Vernon S. Pankratz,Wayne W. Poon,Joseph F. Quinn,Joseph F. Quinn,Andrew J. Saykin,Lon S. Schneider,Amanda Smith,Joshua A. Sonnen,Joshua A. Sonnen,Robert S. Stern,Vivianna M. Van Deerlin,Linda J. Van Eldik,Denise Harold,Giancarlo Russo,David C. Rubinsztein,Anthony Bayer,Magda Tsolaki,Petra Proitsi,Nick C. Fox,Nick C. Fox,Harald Hampel,Michael John Owen,Simon Mead,Peter Passmore,Kevin Morgan,Markus M. Noethen,Martin N. Rossor,Michelle K. Lupton,Michelle K. Lupton,Per Hoffmann,Johannes Kornhuber,Brian A. Lawlor,Andrew McQuillin,Ammar Al-Chalabi,Ammar Al-Chalabi,Joshua C. Bis,Agustín Ruiz,Mercè Boada,Sudha Seshadri,Sudha Seshadri,Alexa S. Beiser,Kenneth Rice,Sven J. van der Lee,Philip L. De Jager,Daniel H. Geschwind,Matthias Riemenschneider,Steffi G. Riedel-Heller,Jerome I. Rotter,Gerhard Ransmayr,Bradley T. Hyman,Carlos Cruchaga,Montserrat Alegret,Bendik S. Winsvold,Priit Palta,Priit Palta,K.-H. Farh,K.-H. Farh,E. Cuenca-Leon,E. Cuenca-Leon,Nicholas A. Furlotte,Tobias Kurth,Lannie Ligthart,Gisela M. Terwindt,Tobias Freilinger,Tobias Freilinger,Caroline Ran,Scott D. Gordon,Guntram Borck,Hieab H.H. Adams,Terho Lehtimäki,Juho Wedenoja,Julie E. Buring,Markus Schuerks,Maria Gudlaug Hrafnsdottir,Jouke-Jan Hottenga,Brenda W.J.H. Penninx,Ville Artto,Mari A. Kaunisto,Salli Vepsäläinen,Nicholas G. Martin,Grant W. Montgomery,Grant W. Montgomery,Mitja I. Kurki,Eija Hämäläinen,Hailiang Huang,Hailiang Huang,Jie Huang,Cynthia Sandor,Caleb Webber,Caleb Webber,Bertram Müller-Myhsok,Bertram Müller-Myhsok,Stefan Schreiber,Veikko Salomaa,Elizabeth Loehrer,Hartmut Goebel,Alfons Macaya,Patricia Pozo-Rosich,Thomas Hansen,Thomas Werge,Thomas Werge,Jaakko Kaprio,Andres Metspalu,Christian Kubisch,Michel D. Ferrari,Andrea Carmine Belin,Arn M. J. M. van den Maagdenberg,John-Anker Zwart,Dorret I. Boomsma,Nicholas Eriksson,Jes Olesen,Daniel I. Chasman,Daniel I. Chasman,Dale R. Nyholt,Andreja Avbersek,Larry Baum,Samuel F. Berkovic,Jonathan P. Bradfield,Russell J. Buono,Russell J. Buono,Russell J. Buono,Claudia B. Catarino,Claudia B. Catarino,Patrick Cossette,Peter De Jonghe,Chantal Depondt,Dennis J. Dlugos,Dennis J. Dlugos,Thomas N. Ferraro,Thomas N. Ferraro,Jacqueline A. French,Helle Hjalgrim,Jennifer Jamnadas-Khoda,Jennifer Jamnadas-Khoda,Reetta Kälviäinen,Wolfram S. Kunz,Holger Lerche,Costin Leu,Dick Lindhout,Dick Lindhout,Warren D. Lo,Warren D. Lo,Daniel H. Lowenstein,Mark McCormack,Mark McCormack,Rikke S. Møller,Anne M. Molloy,Ping-Wing Ng,Karen Oliver,Michael Privitera,Rodney A. Radtke,Ann-Kathrin Ruppert,Thomas Sander,Steven C. Schachter,Steven C. Schachter,Christoph J. Schankin,Christoph J. Schankin,Ingrid E. Scheffer,Ingrid E. Scheffer,Susanne Schoch,Sanjay M. Sisodiya,Philip E. M. Smith,Michael R. Sperling,Pasquale Striano,Rainer Surges,Rainer Surges,G. Neil Thomas,Frank Visscher,Christopher D. Whelan,Federico Zara,Erin L. Heinzen,Anthony G Marson,Anthony G Marson,Felicitas Becker,H. Stroink,Fritz Zimprich,Thomas Gasser,Thomas Gasser,Raphael Gibbs,Peter Heutink,Peter Heutink,Maria Martinez,Maria Martinez,Huw R. Morris,Manu Sharma,Mina Ryten,Kin Y. Mok,Kin Y. Mok,Sara L. Pulit,Sara L. Pulit,Sara L. Pulit,Steve Bevan,Elizabeth G. Holliday,John Attia,Thomas W.K. Battey,Giorgio B. Boncoraglio,Vincent Thijs,Wei-Min Chen,Braxton D. Mitchell,Braxton D. Mitchell,Peter M. Rothwell,Pankaj Sharma,Pankaj Sharma,Cathie Sudlow,Astrid M. Vicente,Hugh S. Markus,Christina Kourkoulis,Christina Kourkoulis,Joana Pera,Miriam R. Raffeld,Scott Silliman,Vesna Boraska Perica,Laura M. Thornton,Laura M. Huckins,N. William Rayner,N. William Rayner,Cathryn M. Lewis,Mònica Gratacòs,Filip Rybakowski,Anna Keski-Rahkonen,Anu Raevuori,Anu Raevuori,James I. Hudson,Ted Reichborn-Kjennerud,Ted Reichborn-Kjennerud,Palmiero Monteleone,Andreas Karwautz,Katrin Männik,Katrin Männik,Jessica H. Baker,Julie K. O'Toole,Sara E. Trace,Oliver S. P. Davis,Sietske G. Helder,Stefan Ehrlich,Beate Herpertz-Dahlmann,Unna N. Danner,Annemarie A. van Elburg,Maurizio Clementi,Monica Forzan,Elisa Docampo,Jolanta Lissowska,Joanna Hauser,Alfonso Tortorella,Mario Maj,Fragiskos Gonidakis,Konstantinos Tziouvas,Hana Papezova,Zeynep Yilmaz,Gudrun Wagner,Sarah Cohen-Woods,Stefan Herms,Antonio Julià,Raquel Rabionet,Danielle M. Dick,Samuli Ripatti,Samuli Ripatti,Ole A. Andreassen,Ole A. Andreassen,Thomas Espeseth,Thomas Espeseth,Astri J. Lundervold,Vidar M. Steen,Vidar M. Steen,Dalila Pinto,Stephen W. Scherer,Stephen W. Scherer,Harald N. Aschauer,Alexandra Schosser,Lars Alfredsson,Leonid Padyukov,Katherine A. Halmi,James E. Mitchell,Michael Strober,Andrew W. Bergen,Walter H. Kaye,Jin P. Szatkiewicz,Bru Cormand,Josep Antoni Ramos-Quiroga,Cristina Sánchez-Mora,Cristina Sánchez-Mora,Marta Ribasés,Marta Ribasés,Miguel Casas,Amaia Hervás,Maria Arranz,Jan Haavik,Jan Haavik,Tetyana Zayats,Tetyana Zayats,Stefan Johansson,Stefan Johansson,Nigel Williams,Astrid Dempfle,Aribert Rothenberger,Jonna Kuntsi,Robert D. Oades,Tobias Banaschewski,Barbara Franke,Jan K. Buitelaar,Alejandro Arias Vasquez,Alysa E. Doyle,Andreas Reif,Klaus-Peter Lesch,Klaus-Peter Lesch,Klaus-Peter Lesch,Christine M. Freitag,Olga Rivero,Haukur Palmason,Marcel Romanos,Kate Langley,Marcella Rietschel,Stephanie H. Witt,Soeren Dalsgaard,Soeren Dalsgaard,Anders D. Børglum,Irwin D. Waldman,Beth Wilmot,Nikolas Molly,Claiton H.D. Bau,Jennifer Crosbie,Russell Schachar,Russell Schachar,Sandra K.,James J. McGough,Eugenio H. Grevet,Sarah E. Medland,Elise B. Robinson,Elise B. Robinson,Lauren A. Weiss,Elena Bacchelli,Anthony J. Bailey,Vanessa H. Bal,Agatino Battaglia,Catalina Betancur,Patrick Bolton,Rita M. Cantor,Patrícia B. S. Celestino-Soper,Geraldine Dawson,Silvia De Rubeis,Frederico Duque,Andrew Green,Andrew Green,Sabine M. Klauck,Marion Leboyer,Marion Leboyer,Pat Levitt,Pat Levitt,Elena Maestrini,Shrikant M. Mane,Daniel Moreno-De-Luca,Daniel Moreno-De-Luca,Jeremy R. Parr,Jeremy R. Parr,Jeremy R. Parr,Regina Regan,Abraham Reichenberg,Sven Sandin,Sven Sandin,Jacob A. S. Vorstman,Thomas H. Wassink,Ellen M. Wijsman,Edwin H. Cook,Susan L. Santangelo,Susan L. Santangelo,Richard Delorme,Richard Delorme,Bernadette Rogé,Bernadette Rogé,Tiago R. Magalhaes,Dan E. Arking,Thomas G. Schulze,Robert C. Thompson,Robert C. Thompson,Jana Strohmaier,Keith Matthews,Keith Matthews,Ingrid Melle,Ingrid Melle,Derek W. Morris,Douglas Blackwood,Andrew M. McIntosh,Sarah E. Bergen,Martin Schalling,Martin Schalling,Stéphane Jamain,Stéphane Jamain,Anna Maaser,Anna Maaser,Sascha B. Fischer,Sascha B. Fischer,Céline S. Reinbold,Céline S. Reinbold,Janice M. Fullerton,Janice M. Fullerton,Jose Guzman-Parra,Fermín Mayoral,Peter R. Schofield,Peter R. Schofield,Sven Cichon,Sven Cichon,Sven Cichon,Thomas W. Mühleisen,Thomas W. Mühleisen,Franziska Degenhardt,Johannes Schumacher,Michael Bauer,Philip B. Mitchell,Philip B. Mitchell,Elliot S. Gershon,John P. Rice,James B. Potash,Peter P. Zandi,Nicholas John Craddock,I. Nicol Ferrier,Martin Alda,Martin Alda,Guy A. Rouleau,Guy A. Rouleau,Gustavo Turecki,Roel A. Ophoff,Carlos N. Pato,Adebayo Anjorin,Eli A. Stahl,Eli A. Stahl,Markus Leber,Piotr M. Czerski,Cristiana Cruceanu,Ian Jones,Danielle Posthuma,Danielle Posthuma,Till F. M. Andlauer,Till F. M. Andlauer,Andreas J. Forstner,Fabian Streit,Bernhard T. Baune,Tracy Air,Grant Sinnamon,Grant Sinnamon,Naomi R. Wray,Donald J. MacIntyre,David J. Porteous,Georg Homuth,Margarita Rivera,Margarita Rivera,Jakob Grove,Christel M. Middeldorp,Christel M. Middeldorp,Christel M. Middeldorp,Ian B. Hickie,Michele L. Pergadia,Divya Mehta,Divya Mehta,Johannes H. Smit,Johannes H. Smit,Rick Jansen,Eco J. C. de Geus,Eco J. C. de Geus,Erin C. Dunn,Qingqin S. Li,Matthias Nauck,Robert A. Schoevers,Aartjan T.F. Beekman,James A. Knowles,Alexander Viktorin,Paul D. Arnold,Paul D. Arnold,Cathy L. Barr,Cathy L. Barr,Cathy L. Barr,Gabriel Bedoya-Berrio,O. Joseph Bienvenu,Helena Brentani,Christie L. Burton,Beatriz Camarena,Carolina Cappi,Danielle C. Cath,Maria Cristina Cavallini,Daniele Cusi,Sabrina M. Darrow,Damiaan Denys,Damiaan Denys,Eske M. Derks,Andrea Dietrich,Andrea Dietrich,Thomas V. Fernandez,Martijn Figee,Martijn Figee,Nelson B. Freimer,Gloria Gerber,Marco A. Grados,Erica Greenberg,Gregory L. Hanna,Andreas Hartmann,Matthew E. Hirschtritt,Pieter J. Hoekstra,Alden Y. Huang,Alden Y. Huang,Chaim Huyser,Cornelia Illmann,Michael A. Jenike,Samuel Kuperman,Bennett L. Leventhal,Christine Lochner,Gholson J. Lyon,Fabio Macciardi,Marcos Madruga-Garrido,Irene A. Malaty,Athanasios Maras,Lauren M. McGrath,Euripedes Constantino Miguel,Pablo Mir,Gerald Nestadt,Humberto Nicolini,Michael S. Okun,Andrew J. Pakstis,Peristera Paschou,John Piacentini,Christopher Pittenger,Kerstin J. Plessen,Kerstin J. Plessen,Vasily Ramensky,Eliana Marisa Ramos,Victor I. Reus,Margaret A. Richter,Margaret A. Richter,Mark A. Riddle,Mary M. Robertson,Veit Roessner,Maria Conceição do Rosário,Maria Conceição do Rosário,Jack Samuels,Paul Sandor,Paul Sandor,Dan J. Stein,Dan J. Stein,Fotis Tsetsos,Filip Van Nieuwerburgh,Sarah Weatherall,Jens R. Wendland,Tomasz Wolańczyk,Yulia Worbe,Gwyneth Zai,Fernando S. Goes,Nicole C.R. McLaughlin,Nicole C.R. McLaughlin,Paul S. Nestadt,Hans-Jörgen Grabe,Christel Depienne,Christel Depienne,Christel Depienne,Anuar Konkashbaev,Nuria Lanzagorta,Ana Victoria Valencia-Duarte,Ana Victoria Valencia-Duarte,Elvira Bramon,Nancy G. Buccola,Wiepke Cahn,Murray J. Cairns,Siow A. Chong,David Cohen,Benedicto Crespo-Facorro,Benedicto Crespo-Facorro,James J. Crowley,Michael Davidson,Lynn E. DeLisi,Lynn E. DeLisi,Timothy G. Dinan,Gary Donohoe,Elodie Drapeau,Jubao Duan,Jubao Duan,Lieuwe de Haan,David M. Hougaard,Sena Karachanak-Yankova,Andrey Khrunin,Janis Klovins,Vaidutis Kučinskas,Jimmy Lee Chee Keong,Svetlana A. Limborska,Carmel M. Loughland,Jouko Lönnqvist,Jouko Lönnqvist,Brion S. Maher,Manuel Mattheisen,Manuel Mattheisen,Colm McDonald,Kieran C. Murphy,Igor Nenadic,Jim van Os,Jim van Os,Jim van Os,Christos Pantelis,Christos Pantelis,Michele T. Pato,Tracey L. Petryshen,Tracey L. Petryshen,Digby Quested,Digby Quested,Panos Roussos,Alan R. Sanders,Alan R. Sanders,Ulrich Schall,Sibylle G. Schwab,Kang Sim,Kang Sim,Hon-Cheong So,Hon-Cheong So,Elisabeth Stoegmann,Elisabeth Stoegmann,Mythily Subramaniam,Draga Toncheva,John L. Waddington,James T.R. Walters,Mark Weiser,Mark Weiser,Wei Cheng,Robert C. Cloninger,David Curtis,David Curtis,Pablo V. Gejman,Pablo V. Gejman,Frans Henskens,Morten Mattingsdal,Sang-Yun Oh,Sang-Yun Oh,Rodney J. Scott,Rodney J. Scott,Bradley T. Webb,Gerome Breen,Claire Churchhouse,Claire Churchhouse,Cynthia M. Bulik,Cynthia M. Bulik,Mark J. Daly,Mark J. Daly,Martin Dichgans,Stephen V. Faraone,Rita Guerreiro,Peter Holmans,Kenneth S. Kendler,Bobby P. C. Koeleman,Carol A. Mathews,Alkes L. Price,Alkes L. Price,Jeremiah M. Scharf,Pamela Sklar,Julie Williams,Nicholas W. Wood,Chris Cotsapas,Chris Cotsapas,Aarno Palotie,Jordan W. Smoller,Jordan W. Smoller,Patrick F. Sullivan,Jonathan Rosand,Aiden Corvin,Aiden Corvin,Benjamin M. Neale,Benjamin M. Neale +720 more
TL;DR: It is demonstrated that, in the general population, the personality trait neuroticism is significantly correlated with almost every psychiatric disorder and migraine, and it is shown that both psychiatric and neurological disorders have robust correlations with cognitive and personality measures.
Journal ArticleDOI
Mapping autism risk loci using genetic linkage and chromosomal rearrangements
Peter Szatmari,Andrew D. Paterson,Lonnie Zwaigenbaum,Wendy Roberts,Jessica Brian,Xiao-Qing Liu,John B. Vincent,Jennifer Skaug,Ann P. Thompson,Lili Senman,Lars Feuk,Cheng Qian,Susan E. Bryson,Marshall B. Jones,Christian R. Marshall,Stephen W. Scherer,Veronica J. Vieland,Christopher W. Bartlett,La Vonne Mangin,Rhinda Goedken,Alberto M. Segre,Margaret A. Pericak-Vance,Michael L. Cuccaro,John R. Gilbert,Harry H. Wright,Ruth K. Abramson,Catalina Betancur,Thomas Bourgeron,Christopher Gillberg,Marion Leboyer,Joseph D. Buxbaum,Kenneth L. Davis,Eric Hollander,Jeremy M. Silverman,Joachim Hallmayer,Linda Lotspeich,James S. Sutcliffe,Jonathan L. Haines,Susan E. Folstein,Joseph Piven,Thomas H. Wassink,Val C. Sheffield,Daniel H. Geschwind,Maja Bucan,W. Ted Brown,Rita M. Cantor,John N. Constantino,T. Conrad Gilliam,Martha R. Herbert,Clara Lajonchere,David H. Ledbetter,Christa Lese-Martin,Janet Miller,Stan F. Nelson,Carol A. Samango-Sprouse,Sarah J. Spence,Matthew W. State,Rudolph E. Tanzi,Hilary Coon,Geraldine Dawson,Bernie Devlin,Annette Estes,Pamela Flodman,Lambertus Klei,William M. McMahon,Nancy J. Minshew,Jeff Munson,Elena Korvatska,Elena Korvatska,Patricia M. Rodier,Gerard D. Schellenberg,Gerard D. Schellenberg,Moyra Smith,M. Anne Spence,Christopher J. Stodgell,Ping Guo Tepper,Ellen M. Wijsman,Chang En Yu,Chang En Yu,Bernadette Rogé,Carine Mantoulan,Kerstin Wittemeyer,Annemarie Poustka,Bärbel Felder,Sabine M. Klauck,Claudia Schuster,Fritz Poustka,Sven Bölte,Sabine Feineis-Matthews,Evelyn Herbrecht,Gabi Schmötzer,John Tsiantis,Katerina Papanikolaou,Elena Maestrini,Elena Bacchelli,Francesca Blasi,Simona Carone,Claudio Toma,Herman van Engeland,Maretha de Jonge,Chantal Kemner,Frederike Koop,Marjolijn Langemeijer,Channa Hijimans,Wouter G. Staal,Gillian Baird,Patrick Bolton,Michael Rutter,Emma Weisblatt,Jonathan Green,Catherine Aldred,Julie Anne Wilkinson,Andrew Pickles,Ann Le Couteur,Tom Berney,Helen McConachie,Anthony J. Bailey,Kostas Francis,Gemma Honeyman,Aislinn Hutchinson,Jeremy R. Parr,Simon Wallace,Anthony P. Monaco,Gabrielle Barnby,Kazuhiro Kobayashi,Janine A. Lamb,Inês Sousa,Nuala Sykes,Edwin H. Cook,Stephen J. Guter,Bennett L. Leventhal,Jeff Salt,Catherine Lord,Christina Corsello,Vanessa Hus,Daniel E. Weeks,Fred R. Volkmar,Maïté Tauber,Eric Fombonne,Andy Shih +139 more
TL;DR: Linkage and copy number variation analyses implicate chromosome 11p12–p13 and neurexins, respectively, among other candidate loci, highlighting glutamate-related genes as promising candidates for contributing to ASDs.