L
Leslie Amos
Researcher at Research Triangle Park
Publications - 2
Citations - 173
Leslie Amos is an academic researcher from Research Triangle Park. The author has contributed to research in topics: Genome-wide association study & Framingham Heart Study. The author has an hindex of 2, co-authored 2 publications receiving 160 citations.
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Journal ArticleDOI
Common genetic variation and susceptibility to partial epilepsies: a genome-wide association study
Dalia Kasperavičiūtė,Claudia B. Catarino,Erin L. Heinzen,Chantal Depondt,Gianpiero L. Cavalleri,Luis O. Caboclo,Sarah K. Tate,Jenny Jamnadas-Khoda,Krishna Chinthapalli,Lisa M. S. Clayton,Kevin V. Shianna,Rodney A. Radtke,Mohamad A. Mikati,William Gallentine,Aatif M. Husain,Saud Alhusaini,David Leppert,David Leppert,Lefkos T. Middleton,Lefkos T. Middleton,Rachel A. Gibson,Marvin Johnson,Paul M. Matthews,Paul M. Matthews,David A. Hosford,Kjell Heuser,Leslie Amos,Marcos Ortega,Dominik Zumsteg,Heinz Gregor Wieser,Bernhard J. Steinhoff,Günter Krämer,Jörg Hansen,Thomas Dorn,Anne-Mari Kantanen,Leif Gjerstad,Leif Gjerstad,Terhi Peuralinna,Dena G. Hernandez,Kai Eriksson,Reetta Kälviäinen,Colin P. Doherty,Nicholas W. Wood,Massimo Pandolfo,John S. Duncan,Josemir W. Sander,Norman Delanty,David Goldstein,Sanjay M. Sisodiya +48 more
TL;DR: It is shown that, at best, common genetic variation can only have a modest role in predisposition to the partial epilepsies when considered across syndromes in Europeans, and research efforts should also be directed towards identifying the multiple rare variants likely to account for at least part of the heritability of the partial seizures.
Journal ArticleDOI
Plasma lipoprotein-associated phospholipase A2 activity in Alzheimer's disease, amnestic mild cognitive impairment, and cognitively healthy elderly subjects: a cross-sectional study
Julie E. Davidson,Julie E. Davidson,Andrew Lockhart,Leslie Amos,Heide A. Stirnadel-Farrant,Vincent Mooser,Marc Sollberger,Axel Regeniter,Andreas U. Monsch,Michael C. Irizarry +9 more
TL;DR: The main clinical correlates of Lp-PLA2 activity in AD, aMCI and cognitively healthy subjects were variables associated with lipid metabolism, and apolipoprotein E (APOE) genotype.