Li Zhang

TL;DR: The proteomic stratification of early-stage hepatocellular carcinoma presented in this study provides insight into the tumour biology of this cancer, and suggests opportunities for personalized therapies that target it.

TL;DR: Global transcriptomic analysis showed that activation of Hedgehog signaling in the Ag subclass may play key roles in tumor development of aggressive HCC, and GLI1, a key transcriptional regulator of hedgehog signaling upregulated in theAg subclass, may be a potential prognostic biomarker and therapeutic target for Ag subclass HCC patients.

TL;DR: The potentials and challenges of using these valuable tools, either alone or in combination, to interrogate critical issues with ovarian cancer have been discussed in this article , where the authors focus on the potential of using them to bridge the gap between laboratory experiments and clinical practice.

TL;DR: A 10-protein diagnostic panel by the random forest model was developed that was able to distinguish acute appendicitis from confusable acute abdomens with high specificity, which indicated the clinical application potential of noninvasive urinary markers in disease diagnosis.