L
Lieve Brochez
Researcher at Ghent University Hospital
Publications - 96
Citations - 3426
Lieve Brochez is an academic researcher from Ghent University Hospital. The author has contributed to research in topics: Melanoma & Medicine. The author has an hindex of 32, co-authored 81 publications receiving 2907 citations.
Papers
More filters
Journal ArticleDOI
The rationale of indoleamine 2,3-dioxygenase inhibition for cancer therapy.
TL;DR: Current available data on the role of IDO in cancer and the current results obtained with IDO inhibition are reviewed, both in animal models and in phase 1 and 2 clinical trials in humans.
Journal ArticleDOI
Identification of a ZEB2-MITF-ZEB1 transcriptional network that controls melanogenesis and melanoma progression.
Geertrui Denecker,Niels Vandamme,Özden Akay,Dana Koludrovic,Joachim Taminau,Kelly Lemeire,Alexander Gheldof,B De Craene,M. Van Gele,Lieve Brochez,Girish Mallya Udupi,Mairin Rafferty,Balázs Bálint,William M. Gallagher,Ghanem Elias Ghanem,Danny Huylebroeck,Danny Huylebroeck,Jody J. Haigh,J. J. Van Den Oord,Lionel Larue,Irwin Davidson,J-C Marine,Geert Berx +22 more
TL;DR: A transcriptional signaling network in which the EMT transcription factor ZEB2 regulates MITF levels to control melanocyte differentiation is identified and is relevant for human melanomagenesis as loss of Zeb2 expression is associated with reduced patient survival.
Journal ArticleDOI
Quality of life and stigmatization profile in a cohort of vitiligo patients and effect of the use of camouflage.
TL;DR: Camouflage can be recommended, particularly in patients with higher DLQI scores or self-assessed disease severity, and patients with minor involvement of the face benefit from camouflage.
Book Chapter
Hypomelanoses and hypermelanoses
Hilde Lapeere,Barbara Boone,Sofie De Schepper,Evelien Verhaeghe,Katia Ongenae,Nanja van Geel,Jo Lambert,Lieve Brochez,Jean-Marie Naeyaert +8 more
TL;DR: The Griscelli syndrome presents in accelerated phase with neurological involvement and the role of mutations in the RAB27A gene as an indication for BMT is unclear.
Journal ArticleDOI
Serological markers for melanoma.
Lieve Brochez,Jean Naeyaert +1 more
TL;DR: Results for cytokines, cytokine receptors, cell adhesion molecules, S100 protein, melanoma inhibitory activity, tissue‐specific reverse transcription–polymerase chain reaction, neurone‐specific enolase, lipid‐bound sialic acid and melanin metabolites such as 5‐S‐cysteinyldopa and 6‐hydroxy‐5‐methoxyindole‐2‐carboxylic acid are discussed.