L
Liisa Nissinen
Researcher at University of Turku
Publications - 57
Citations - 2250
Liisa Nissinen is an academic researcher from University of Turku. The author has contributed to research in topics: Integrin & Collagen receptor. The author has an hindex of 26, co-authored 46 publications receiving 2007 citations. Previous affiliations of Liisa Nissinen include University of Jyväskylä & Turku University Hospital.
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Journal ArticleDOI
Collagenase-3 (MMP-13) is expressed by hypertrophic chondrocytes, periosteal cells, and osteoblasts during human fetal bone development.
Nina Johansson,Ulpu Saarialho-Kere,Kristiina Airola,Riitta Herva,Liisa Nissinen,Jukka Westermarck,Eero Vuorio,Jyrki Heino,Veli-Matti Kähäri +8 more
TL;DR: The results suggest that MMP‐13 plays an important role in the extracellular matrix remodeling during fetal bone development both via endochondral and intramembranous ossification.
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Selective Binding of Collagen Subtypes by Integrin α1I, α2I, and α10I Domains
Mira Tulla,Olli T. Pentikäinen,Tiina Viitasalo,Jarmo Käpylä,Ulla Impola,Petri Nykvist,Liisa Nissinen,Liisa Nissinen,Mark S. Johnson,Jyrki Heino,Jyrki Heino +10 more
TL;DR: All three collagen receptors appear to differ in their ability to recognize distinct collagen subtypes, and the relatively small structural differences on their collagen binding surfaces may explain the functional specifics.
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Internalization of Echovirus 1 in Caveolae
Varpu Marjomäki,Vilja Pietiäinen,Heli Matilainen,Paula Upla,Johanna Ivaska,Liisa Nissinen,Hilkka Reunanen,Pasi Huttunen,Pasi Huttunen,Timo Hyypiä,Jyrki Heino,Jyrki Heino +11 more
TL;DR: The expression of dominant negative caveolin in cells markedly inhibited EV1 infection, indicating the importance of caveolae for the viral replication cycle of EV1.
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Integrin α2β1 Promotes Activation of Protein Phosphatase 2A and Dephosphorylation of Akt and Glycogen Synthase Kinase 3β
TL;DR: Results indicate that cell adhesion to collagen modulates Akt activity via the α2β1-induced activation of PP2A, which is a downstream effector protein of phosphatidylinositol-3-kinase (PI-3K).
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Complement Factor H: A Biomarker for Progression of Cutaneous Squamous Cell Carcinoma
Pilvi Riihilä,Pilvi Riihilä,Liisa Nissinen,Liisa Nissinen,Risto Ala-aho,Risto Ala-aho,Markku Kallajoki,Reidar Grenman,Seppo Meri,Sirkku Peltonen,Juha Peltonen,Veli-Matti Kähäri,Veli-Matti Kähäri +12 more
TL;DR: Evidence is provided for a role of CFH and FHL-1 in cSCC progression and they are identified as progression markers and potential therapeutic targets in SCCs of skin.