L
Lili Ding
Researcher at Princess Margaret Cancer Centre
Publications - 33
Citations - 1073
Lili Ding is an academic researcher from Princess Margaret Cancer Centre. The author has contributed to research in topics: Chemistry & Medicine. The author has an hindex of 14, co-authored 25 publications receiving 880 citations. Previous affiliations of Lili Ding include University of Toronto & University Health Network.
Papers
More filters
Journal ArticleDOI
Biomimetic Nanocarrier for Direct Cytosolic Drug Delivery
Zhihong Zhang,Weiguo Cao,Weiguo Cao,Honglin Jin,Honglin Jin,Jonathan F. Lovell,Mi Yang,Lili Ding,Juan Chen,Ian R. Corbin,Qingming Luo,Gang Zheng +11 more
TL;DR: The ability to transport a large quantity of drug molecules into cytosolic compartments of cancer cells has powerful implications in modern molecular therapeutics because the sites of action of the drugs are often cytosol organelles.
Journal ArticleDOI
A PEGylation-Free Biomimetic Porphyrin Nanoplatform for Personalized Cancer Theranostics.
Liyang Cui,Liyang Cui,Liyang Cui,Qiaoya Lin,Cheng S. Jin,Cheng S. Jin,Wenlei Jiang,Huang Huang,Lili Ding,Nidal Muhanna,Nidal Muhanna,Jonathan C. Irish,Jonathan C. Irish,Fan Wang,Juan Chen,Gang Zheng +15 more
TL;DR: PLP offers a biomimetic theranostic nanoplatform for pretreatment stratification using PET and NIR fluorescence imaging and for further customized cancer management via imaging-guided surgery, PDT, or/and potential chemotherapy.
Journal ArticleDOI
HDL-mimicking peptide-lipid nanoparticles with improved tumor targeting.
Zhihong Zhang,Zhihong Zhang,Juan Chen,Lili Ding,Honglin Jin,Honglin Jin,Jonathan F. Lovell,Ian R. Corbin,Weiguo Cao,Weiguo Cao,Pui-Chi Lo,Mi Yang,Ming-Sound Tsao,Qingming Luo,Gang Zheng,Gang Zheng +15 more
TL;DR: By adding targeting ligands to nanoparticles that mimic high-density lipoprotein (HDL), tumor-targeted sub-30-nm peptide-lipid nanocarriers are created with controllable size, cargo loading, and shielding properties.
Journal ArticleDOI
Efficient cytosolic delivery of siRNA using HDL-mimicking nanoparticles.
Mi Yang,Honglin Jin,Honglin Jin,Honglin Jin,Juan Chen,Lili Ding,Kenneth K. Ng,Kenneth K. Ng,Qiaoya Lin,Qiaoya Lin,Qiaoya Lin,Jonathan F. Lovell,Jonathan F. Lovell,Zhihong Zhang,Zhihong Zhang,Zhihong Zhang,Gang Zheng,Gang Zheng +17 more
TL;DR: Therapeutic application of RNA interference requires delivery of siRNAs into the cytoplasm of targeted cells and tissues, where they are recognized and associated with RNA-induced silencing complex (RISC) to perform their function.
Journal ArticleDOI
Synthesis and evaluation of a stable bacteriochlorophyll-analog and its incorporation into high-density lipoprotein nanoparticles for tumor imaging.
Weiguo Cao,Kenneth K. Ng,Ian R. Corbin,Zhihong Zhang,Zhihong Zhang,Lili Ding,Juan Chen,Gang Zheng +7 more
TL;DR: A robust synthesis of a novel Bchl analog, bacteriochlorin e(6) bisoleate (BchlBOA), which is chemically stable, has excellent photophysical properties and is tailored for the incorporation into a tumor targetable high-density lipoprotein (HDL)-like nanoparticle (NP).