L
Linbo Liu
Researcher at Nanyang Technological University
Publications - 166
Citations - 2871
Linbo Liu is an academic researcher from Nanyang Technological University. The author has contributed to research in topics: Optical coherence tomography & Medicine. The author has an hindex of 24, co-authored 135 publications receiving 2149 citations. Previous affiliations of Linbo Liu include National University of Singapore & Harvard University.
Papers
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Journal ArticleDOI
Imaging the subcellular structure of human coronary atherosclerosis using micro–optical coherence tomography
Linbo Liu,Joseph A. Gardecki,Seemantini K. Nadkarni,Seemantini K. Nadkarni,Jimmy Toussaint,Yukako Yagi,Brett E. Bouma,Brett E. Bouma,Guillermo J. Tearney,Guillermo J. Tearney +9 more
TL;DR: It is shown that μOCT images of cadaver coronary arteries provide clear pictures of cellular and subcellular features associated with atherogenesis, thrombosis and responses to interventional therapy, and suggests that μ OCT can complement existing diagnostic techniques for investigating atherosclerotic specimens, and may eventually become a useful tool for cellular andSubcellular characterization of the human coronary wall in vivo.
Journal ArticleDOI
A Swellable Microneedle Patch to Rapidly Extract Skin Interstitial Fluid for Timely Metabolic Analysis.
Hao Chang,Mengjia Zheng,Xiaojun Yu,Aung Than,Razina Z. Seeni,Rongjie Kang,Jingqi Tian,Duong Phan Khanh,Linbo Liu,Peng Chen,Chenjie Xu +10 more
TL;DR: A swellable MN patch that can rapidly extract ISF is developed and can be efficiently recovered from MN patch by centrifugation for the subsequent offline analysis of metabolites such as glucose and cholesterol.
Journal ArticleDOI
Method for quantitative study of airway functional microanatomy using micro-optical coherence tomography.
Linbo Liu,Kengyeh K. Chu,Grace H. Houser,Bradford Diephuis,Bradford Diephuis,Yao Li,Eric J. Wilsterman,Suresh Shastry,Gregory Dierksen,Susan E. Birket,Marina Mazur,Suzanne Byan-Parker,William E. Grizzle,Eric J. Sorscher,Steven M. Rowe,Guillermo J. Tearney,Guillermo J. Tearney +16 more
TL;DR: The use of a high resolution form of optical coherence tomography, termed micro-OCT (μOCT), for investigating the functional microanatomy of airway epithelia reveals distinguishable phases of the ciliary stroke pattern and glandular extrusion.
Journal ArticleDOI
A Functional Anatomic Defect of the Cystic Fibrosis Airway
Susan E. Birket,Kengyeh K. Chu,Linbo Liu,Grace H. Houser,Bradford Diephuis,Eric J. Wilsterman,Gregory Dierksen,Marina Mazur,Suresh Shastry,Yao Li,John D. Watson,Alexander T. Smith,Benjamin S. Schuster,Justin Hanes,William E. Grizzle,Eric J. Sorscher,Guillermo J. Tearney,Steven M. Rowe +17 more
TL;DR: An inherent defect in CF airway surface liquid contributes to delayed MCT beyond that caused by airway dehydration alone and identifies a fundamental mechanism underlying the pathogenesis of CF lung disease in the absence of antecedent infection or inflammation.
Journal ArticleDOI
Gravity-driven membrane filtration as pretreatment for seawater reverse osmosis: linking biofouling layer morphology with flux stabilization.
Ebrahim Akhondi,Bing Wu,Shuyang Sun,Brigit Marxer,Weikang Lim,Jun Gu,Linbo Liu,Michael Burkhardt,Diane McDougald,Wouter Pronk,Anthony G. Fane +10 more
TL;DR: The data suggested pore constriction fouling was predominant at the early stage of filtration, during which the hydrostatic pressure and temperature had negligible effects on permeate flux, and changes in the biofouling layer structure were attributed to the movement and predation behaviour of the eukaryotic organisms.