L
Ling Yang
Researcher at Dalian Institute of Chemical Physics
Publications - 258
Citations - 9731
Ling Yang is an academic researcher from Dalian Institute of Chemical Physics. The author has contributed to research in topics: Docking (molecular) & Quantitative structure–activity relationship. The author has an hindex of 45, co-authored 231 publications receiving 7531 citations. Previous affiliations of Ling Yang include Chinese Academy of Sciences & Jiangxi University of Traditional Chinese Medicine.
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TCMSP: a database of systems pharmacology for drug discovery from herbal medicines.
Jinlong Ru,Peng Li,Wang Jinan,Wei Zhou,Bohui Li,Chao Huang,Pidong Li,Zihu Guo,Weiyang Tao,Yinfeng Yang,Xue Xu,Yan Li,Yonghua Wang,Ling Yang +13 more
TL;DR: The particular strengths of TCMSP are the composition of the large number of herbal entries, and the ability to identify drug-target networks and drug-disease networks, which will help revealing the mechanisms of action of Chinese herbs, uncovering the nature ofTCM theory and developing new herb-oriented drugs.
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Network pharmacology-based prediction of the active ingredients and potential targets of Chinese herbal Radix Curcumae formula for application to cardiovascular disease.
TL;DR: The mechanism of efficiency of Radix Curcumae formula for the prevention of CCVD is explained, and the potential targets of the Chinese medicines are predicted, which facilitates to elucidate the compatible mechanism of the complex prescription, i.e., "jun-chen-zuo-shi".
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P-glycoprotein antibody functionalized carbon nanotube overcomes the multidrug resistance of human leukemia cells.
TL;DR: Ap-SWNTs loaded with drug molecules could be used to suppress the proliferation of multidrug resistant cells, destroy the tumor stem cells, and inhibit the metastasis of tumor.
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Systems approaches and polypharmacology for drug discovery from herbal medicines: an example using licorice.
TL;DR: A novel systems pharmacology model that integrates oral bioavailability screening, drug-likeness evaluation, blood-brain barrier permeation, target identification and network analysis has been established to investigate the herbal medicines.
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Systems pharmacology in drug discovery and therapeutic insight for herbal medicines
TL;DR: The aim of the present work is to highlight the role that the systems pharmacology plays across the traditional herbal medicines discipline, which is exemplified by a case study of botanical drugs applied in the treatment of depression.