Liping Xiong

TL;DR: Atg5-mediated autophagy in proximal epithelial cells is a critical host-defense mechanism that prevents renal fibrosis by blocking G2/M arrest, suggesting the regulation of cell cycle progression by ATG5 is Autophagy dependent.

TL;DR: The results imply that inhibiting p-Drp1S616-mediated mitochondrial fission attenuates fibroblast activation and proliferation in renal fibrosis through epigenetic regulation of fibrosis-related genes transcription and may serve as a therapeutic target for retarding progression of chronic kidney disease.

TL;DR: A lower serum potassium level was associated with all-cause and cardiovascular mortality during the first year of follow-up in incident PD patients and higher variability of serum potassium levels conferred an increased risk of death in this population of patients.

TL;DR: A higher serum TG/HDL-C ratio was associated with an increased risk of all-cause and CVD mortality in PD patients, and this association was significantly higher in female than male PD patients.

TL;DR: The prevalence of pulmonary hypertension at the start of peritoneal dialysis was common and associated with increased risk of both all-cause and cardiovascular mortality in incident PD patients.