L
Luc Malaval
Researcher at Jean Monnet University
Publications - 86
Citations - 7132
Luc Malaval is an academic researcher from Jean Monnet University. The author has contributed to research in topics: Bone remodeling & Bone sialoprotein. The author has an hindex of 44, co-authored 84 publications receiving 6800 citations. Previous affiliations of Luc Malaval include University of Toronto & Lyon College.
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Serum bone gla-protein: a specific marker for bone formation in postmenopausal osteoporosis
TL;DR: Serum BGP appears to be a specific marker for bone formation and can predict the histological profile in PMO and should be valuable in assessing the effects of treatments that increase bone formation.
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Osteoblast and chondroblast differentiation.
TL;DR: This work focuses on the osteoprogenitors that divide and differentiate into mature OBs forming bone nodules in fetal rat calvaria cell cultures, and uses cellular, immunocytochemical, and molecular approaches, including PCR on small numbers of cells, to discriminate stages.
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Cellular expression of bone‐related proteins during in vitro osteogenesis in rat bone marrow stromal cell cultures
TL;DR: The studies indicate that the bone marrow stromal cell system is a useful model to study the temporal and spatial expression of bone‐related proteins during osteogenesis and formation, mineralization, and maturation of bone nodules.
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The T3Rα gene encoding a thyroid hormone receptor is essential for post‐natal development and thyroid hormone production
A. Fraichard,Olivier Chassande,Michelina Plateroti,Jean-Paul Roux,Jacqueline Trouillas,Colette Dehay,Claude Legrand,Karine Gauthier,Michèle Kedinger,Luc Malaval,Bernard Rousset,Jacques Samarut +11 more
TL;DR: The abnormal phenotypes observed on the homozygous mutant mice strongly suggest that the T3Rα gene is essential for the transformation of a mother‐dependent pup to an ‘adult’ mouse.
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Mechanical Loading Down-Regulates Peroxisome Proliferator-Activated Receptor γ in Bone Marrow Stromal Cells and Favors Osteoblastogenesis at the Expense of Adipogenesis
Valentin David,Aline Martin,Marie-Hélène Lafage-Proust,Luc Malaval,Sylvie Peyroche,David Jones,Laurence Vico,Alain Guignandon +7 more
TL;DR: Evidence is provided that mechanical stimuli are potential PPARgamma modulators counteracting adipocyte differentiation and inhibition of osteoblastogenesis.