L
Luciano Belem
Publications - 9
Citations - 1814
Luciano Belem is an academic researcher. The author has contributed to research in topics: Heart failure & Perfusion scanning. The author has an hindex of 5, co-authored 9 publications receiving 1798 citations.
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Journal ArticleDOI
Transendocardial, Autologous Bone Marrow Cell Transplantation for Severe, Chronic Ischemic Heart Failure
Emerson C. Perin,Hans F. Dohmann,Radovan Borojevic,Suzana A. Silva,Andre L.S. Sousa,Claudio Tinoco Mesquita,Maria Isabel D. Rossi,Antonio Carlos Carvalho,Hélio S. Dutra,Hans J.F. Dohmann,Guilherme V. Silva,Luciano Belem,Ricardo Vivacqua,Fernando Oswaldo Dias Rangel,Roberto Esporcatte,Yong-Jian Geng,William K. Vaughn,Joao A.R. Assad,Evandro Tinoco Mesquita,James T. Willerson +19 more
TL;DR: The present study demonstrates the relative safety of intramyocardial injections of bone marrow–derived stem cells in humans with severe heart failure and the potential for improving myocardial blood flow with associated enhancement of regional and global left ventricular function.
Journal ArticleDOI
Improved Exercise Capacity and Ischemia 6 and 12 Months After Transendocardial Injection of Autologous Bone Marrow Mononuclear Cells for Ischemic Cardiomyopathy
Emerson C. Perin,Hans F. Dohmann,Radovan Borojevic,Suzana A. Silva,Andre L.S. Sousa,Guilherme V. Silva,Claudio Tinoco Mesquita,Luciano Belem,William K. Vaughn,Fernando Oswaldo Dias Rangel,Joao A.R. Assad,Antonio Carlos Carvalho,Rodrigo Branco,Maria Isabel D. Rossi,Hans J.F. Dohmann,James T. Willerson +15 more
TL;DR: The 6- and 12-month follow-up data suggest that transendocardial injection of ABMMNCs in patients with end-stage ischemic heart disease may produce a durable therapeutic effect and improve myocardial perfusion and exercise capacity.
Journal ArticleDOI
Functional and Transcriptomic Recovery of Infarcted Mouse Myocardium Treated with Bone Marrow Mononuclear Cells
Stephan Lachtermacher,B.L.B. Esporcatte,Fabio S. A. Fortes,Nazareth N. Rocha,Nazareth N. Rocha,Fabricio Montalvão,Patricia C. Costa,Luciano Belem,Arnaldo Rabischoffisky,Hugo Caire de Castro Faria Neto,Rita Vasconcellos,Dumitru A. Iacobas,Sanda Iacobas,David C. Spray,Neil Thomas,Regina Coeli dos Santos Goldenberg,Antonio Carlos Carvalho,Antonio Carlos Carvalho +17 more
TL;DR: A beneficial role for bone marrow-derived cell therapy is confirmed and new information on molecular mechanisms operating after BMNC transplantation on post ischemic heart failure in mice is provided.
Journal ArticleDOI
Cardiac gene expression and systemic cytokine profile are complementary in a murine model of post-ischemic heart failure
Stephan Lachtermacher,B.L.B. Esporcatte,Fabricio Montalvão,Patricia C. Costa,Deivid C. Rodrigues,Luciano Belem,A. Rabischoffisky,H.C.C. Faria Neto,Rita Vasconcellos,Sanda Iacobas,Dumitru A. Iacobas,H.F.R. Dohmann,David C. Spray,Regina Coeli dos Santos Goldenberg,A.C. Campos-de-Carvalho,A.C. Campos-de-Carvalho +15 more
TL;DR: Data indicate that post-ischemic heart remodeling is accompanied by immune-mediated mechanisms that act both systemically and locally.
Journal ArticleDOI
Cardiovascular effects of SPARK conducted electrical weapon in healthy subjects
Carlos Scherr,Antonio Carlos de Carvalho,Luciano Belem,Luiz Henrique Loyola,Renata Leborato Guerra,Fernanda Blanco,Claudio Martins Mangia +6 more
TL;DR: SPARK brand CEW is effective in incapacitating individuals by the shock of the application time, without causing, adverse events.