Luisa Imberti

TL;DR: The measurement of MxA RNA is simple and useful to detect viral infections and in distinguishing them from acute graft versus host disease after allogeneic cell transplantation, and well correlated with viral infections in follow-up samples.

TL;DR: The occurrence of spontaneous mutations in the constant regions of the T-cell receptor beta chains of T lymphocytes obtained from two babies who underwent in utero transplantation because of severe combined immunodeficiency provides further support indicating that hypermutation ofThe T- cell receptor genes may indeed occur, given the necessary conditions.

TL;DR: In this paper , the authors proposed a genetic risk test for Progressive multifocal leukoencephalopathy (PML), a rare and often lethal brain disorder caused by the common, typically benign polyomavirus 2, also known as JC virus (JCV).

TL;DR: ImmunoTyper-SR is introduced, an algorithmic method for genotype and CNV analysis of the germline IGHV genes using Illumina whole genome sequencing (WGS) data based on a novel combinatorial optimization formulation that aims to minimize the total edit distance between reads and their assigned I GHV alleles from a given database.

TL;DR: The results reinforce the notion of wide inter-regional variations in the frequency of C/T-13910 polymorphism and of incostant concordance with hypolactasic phenotype, even in subjects from the same country.