L
Luyong Zhang
Researcher at China Pharmaceutical University
Publications - 376
Citations - 10021
Luyong Zhang is an academic researcher from China Pharmaceutical University. The author has contributed to research in topics: Triptolide & Liver injury. The author has an hindex of 45, co-authored 335 publications receiving 8064 citations. Previous affiliations of Luyong Zhang include Guangdong Pharmaceutical University.
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Triptolide: Progress on research in pharmacodynamics and toxicology
TL;DR: Triptolide, a biologically active natural product extracted from the root of Tripterygium wilfordii, has shown promising pharmacological effects, particularly as an anti-tumor agent, in traditional Chinese medicine and in anti-cancer research.
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Conjugated bile acids activate the sphingosine-1-phosphate receptor 2 in primary rodent hepatocytes.
Elaine Studer,Xiqiao Zhou,Renping Zhao,Yun Wang,Kazuaki Takabe,Masayuki Nagahashi,William M. Pandak,Paul Dent,Sarah Spiegel,Ruihua Shi,Weiren Xu,Xuyuan Liu,Pat Bohdan,Luyong Zhang,Huiping Zhou,Phillip B. Hylemon +15 more
TL;DR: All these data support the hypothesis that conjugated bile acids activate the ERK1/2 and AKT signaling pathways primarily through S1P2 in primary rodent hepatocytes.
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Naturally Occurring Pentacyclic Triterpenes as Inhibitors of Glycogen Phosphorylase: Synthesis, Structure−Activity Relationships, and X-ray Crystallographic Studies†
Xiaoan Wen,Hongbin Sun,Jun Liu,Keguang Cheng,Pu Zhang,Liying Zhang,Jia Hao,Luyong Zhang,Peizhou Ni,Spyros E. Zographos,Demetres D. Leonidas,K.-M. Alexacou,Thanasis Gimisis,Joseph Hayes,Nikos G. Oikonomakos +14 more
TL;DR: Pentacyclic triterpenes represent a promising class of multiple-target antidiabetic agents that exert hypoglycemic effects, at least in part, through GP inhibition.
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Microglia: Housekeeper of the Central Nervous System.
John Alimamy Kabba,Yazhou Xu,Handson Christian,Wenchen Ruan,Kitchen Chenai,Yun Xiang,Luyong Zhang,Juan M. Saavedra,Tao Pang,Tao Pang +9 more
TL;DR: This review addresses the complex interaction of microglia with each cell type in the brain: neurons, astrocytes, cerebrovascular endothelial cells, and oligodendroCytes and their roles in the development and progression of age-related neurodegenerative disorders.
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Pharmacological evaluation of Alstonia scholaris: Anti-inflammatory and analgesic effects
Jian-Hua Shang,Xiang-Hai Cai,Tao Feng,Yun-Li Zhao,Jing-Kun Wang,Luyong Zhang,Ming Yan,Xiao-Dong Luo +7 more
TL;DR: The alkaloid fraction of Alstonia scholaris leaf, three main alkaloids, picrinine, vallesamine and scholaricine, may produce the anti-inflammatory and analgesic effect peripherally based on several in vivo assays.