M
M A Viganò
Researcher at University of Milan
Publications - 26
Citations - 2198
M A Viganò is an academic researcher from University of Milan. The author has contributed to research in topics: Transcription factor & Promoter. The author has an hindex of 19, co-authored 22 publications receiving 2142 citations. Previous affiliations of M A Viganò include National Institutes of Health & Laboratory of Molecular Biology.
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Journal ArticleDOI
A POU-domain transcription factor in early stem cells and germ cells of the mammalian embryo.
Mitchell H. Rosner,M A Viganò,Keiko Ozato,P. M. Timmons,F. Poirier,F. Poirier,Peter W. J. Rigby,Louis M. Staudt +7 more
TL;DR: The murine oct-3 gene encodes a transcription factor containing a POU-specific domain and a homeodomain, which is expressed in the totipotent and pluripotent stem cells of the pre-gastrulation embryo and is down-regulated during differentiation to endoderm and mesoderm, suggesting that it has a role in early development.
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A novel N-terminal motif for palmitoylation of G-protein alpha subunits.
TL;DR: The post-translational processing of G alpha subunits expressed endogenously in rat PC12 and NG108-15 rat/mouse hybrid cells, and after transfection of cDNA expression constructs into COS cells, suggests that reversible palmitoylation may regulate G alpha localization and function.
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Breast cancer metastases are molecularly distinct from their primary tumors.
Maurizio Vecchi,Stefano Confalonieri,Paolo Nuciforo,M A Viganò,Maria Capra,Marco Bianchi,D Nicosia,Fabrizio Bianchi,Viviana Galimberti,Giuseppe Viale,Giuseppe Palermo,A. Riccardi,Renato Campanini,Maria Grazia Daidone,M. A. Pierotti,Salvatore Pece,P P Di Fiore +16 more
TL;DR: The results show that breast cancer metastases are molecularly distinct from their primary tumors.
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Excitatory amino acid neurotoxicity at the N-methyl-D-aspartate receptor in cultured neurons: pharmacological characterization.
TL;DR: Glutamate toxicity in energy-deprived cerebellar granule cells is mediated by NMDA receptors, and competitive and non-competitive NMDA receptor antagonists completely blocked neurotoxicity due to glutamate and other NMda receptor agonists.
Journal Article
Binding and functional characterization of the cardioselective muscarinic antagonist methoctramine.
TL;DR: The evidence appears to characterize methoctramine as being the most selective M2 muscarinic antagonist described to date.