M
Magesh Sadasivam
Researcher at Harvard University
Publications - 17
Citations - 2405
Magesh Sadasivam is an academic researcher from Harvard University. The author has contributed to research in topics: Singlet oxygen & Drug delivery. The author has an hindex of 16, co-authored 17 publications receiving 1925 citations. Previous affiliations of Magesh Sadasivam include Massachusetts Institute of Technology & Amity University.
Papers
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Journal ArticleDOI
Antimicrobial strategies centered around reactive oxygen species - bactericidal antibiotics, photodynamic therapy and beyond
Fatma Vatansever,Wanessa C.M.A. de Melo,Wanessa C.M.A. de Melo,Pinar Avci,Pinar Avci,Daniela Vecchio,Magesh Sadasivam,Magesh Sadasivam,Asheesh Gupta,Asheesh Gupta,Rakkiyappan Chandran,Rakkiyappan Chandran,Mahdi Karimi,Mahdi Karimi,Nivaldo Antonio Parizotto,Rui Yin,Rui Yin,George P. Tegos,Michael R. Hamblin,Michael R. Hamblin +19 more
TL;DR: Antioxidant defenses against ROS in microbial cells and the use of ROS by antimicrobial host defense systems are covered and reactive nitrogen species and related therapeutics, such as acidified nitrite and nitric oxide-releasing nanoparticles are covered.
Journal Article
Low-level laser (light) therapy (LLLT) in skin: stimulating, healing, restoring.
Pinar Avci,Asheesh Gupta,Magesh Sadasivam,Daniela Vecchio,Zeev Pam,Nadav Pam,Michael R. Hamblin +6 more
TL;DR: Low-level laser (light) therapy (LLLT) is a fast-growing technology used to treat a multitude of conditions that require stimulation of healing, relief of pain and inflammation, and restoration of function.
Journal ArticleDOI
Physical energy for drug delivery; poration, concentration and activation
Shanmugamurthy Lakshmanan,Gaurav K. Gupta,Pinar Avci,Rakkiyappan Chandran,Magesh Sadasivam,Ana Elisa Serafim Jorge,Michael R. Hamblin,Michael R. Hamblin +7 more
TL;DR: Techniques for controlling the rate and duration of drug delivery, while targeting specific locations of the body for treatment, and physical energy forces to enhance drug delivery within the targeted cells or tissues are covered.
Journal ArticleDOI
Photodynamic inactivation of biofilm: taking a lightly colored approach to stubborn infection
Wanessa C.M.A. de Melo,Pinar Avci,Milene Nóbrega de Oliveira,Asheesh Gupta,Daniela Vecchio,Magesh Sadasivam,Rakkiyappan Chandran,Ying-Ying Huang,Rui Yin,Livia Rodrigues Perussi,George P. Tegos,Janice Rodrigues Perussi,Tianhong Dai,Michael R. Hamblin +13 more
TL;DR: Antimicrobial photodynamic therapy (aPDT) as discussed by the authors involves the combination of a nontoxic dye and low-intensity visible light which produces cytotoxic reactive oxygen species.
Journal ArticleDOI
An automated smartphone-based diagnostic assay for point-of-care semen analysis
Manoj Kumar Kanakasabapathy,Magesh Sadasivam,Anupriya Singh,Collin Preston,Prudhvi Thirumalaraju,Maanasa Venkataraman,Charles L. Bormann,Mohamed Shehata Draz,John C. Petrozza,Hadi Shafiee,Hadi Shafiee +10 more
TL;DR: It is demonstrated that a low-cost smartphone accessory can be used for home-based male infertility screening and suggested that the integration of microfluidics, optical sensing accessories, and advances in consumer electronics, particularly smartphone capabilities, can make remote semen quality testing accessible to people in both developed and developing countries who have access to smartphones.