Rui Yin

TL;DR: Antioxidant defenses against ROS in microbial cells and the use of ROS by antimicrobial host defense systems are covered and reactive nitrogen species and related therapeutics, such as acidified nitrite and nitric oxide-releasing nanoparticles are covered.

TL;DR: Photodynamic therapy is the combination of non-toxic photosensitizing dyes with harmless visible light that together produce abundant destructive reactive oxygen species (ROS) and has good specificity for binding to microbial cells while sparing host mammalian cells and can be used for treating many localized infections.

TL;DR: The efficacy of blue light at 415 nm for the treatment of acute, potentially lethal Pseudomonas aeruginosa burn infections in mice is demonstrated and it is suggested that blue light therapy might offer an effective and safe alternative to conventional antimicrobial therapy for P. aerug inosa burns.

TL;DR: The relentless advance of drug-resistance among pathogenic microbes, mandates a search for alternative approaches that will not cause resistance, and this review will cover photocatalytic disinfection with titania nanoparticles, carbon nanomaterials, Carbon nanotubes and graphene, liposomes and polymeric nanoparticles.

TL;DR: Antimicrobial photodynamic therapy (aPDT) as discussed by the authors involves the combination of a nontoxic dye and low-intensity visible light which produces cytotoxic reactive oxygen species.