M
Mahipal G. Sinnollareddy
Researcher at University of South Australia
Publications - 13
Citations - 266
Mahipal G. Sinnollareddy is an academic researcher from University of South Australia. The author has contributed to research in topics: Fluconazole & Intensive care. The author has an hindex of 7, co-authored 13 publications receiving 199 citations. Previous affiliations of Mahipal G. Sinnollareddy include Canberra Hospital.
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Journal ArticleDOI
β-lactam pharmacokinetics and pharmacodynamics in critically ill patients and strategies for dose optimization: a structured review.
TL;DR: The present review describes the strategies for dose optimization of β‐lactams in critically ill patients in line with the PK and PD of these drugs.
Journal ArticleDOI
The Effect of Renal Replacement Therapy and Antibiotic Dose on Antibiotic Concentrations in Critically Ill Patients: Data From the Multinational Sampling Antibiotics in Renal Replacement Therapy Study
Jason A. Roberts,Gavin M. Joynt,Anna Lee,Gordon Y.S. Choi,Rinaldo Bellomo,Salmaan Kanji,Salmaan Kanji,M Yugan Mudaliar,Sandra L. Peake,Sandra L. Peake,Dianne P Stephens,Fabio Silvio Taccone,Marta Ulldemolins,Miia Valkonen,Julius Agbeve,João P Baptista,Vasileios Bekos,Clément Boidin,Clément Boidin,Alexander Brinkmann,Luke Buizen,Pedro Castro,C Louise Cole,C Louise Cole,Jacques Creteur,Jan J. De Waele,Renae Deans,Glenn M Eastwood,Leslie Escobar,Charles D. Gomersall,Rebecca Gresham,Janattul Ain Jamal,Stefan Kluge,Christina König,Christina König,Vasilios P Koulouras,Melissa Lassig-Smith,Pierre-François Laterre,Katie Lei,Patricia Leung,Jean-Yves Lefrant,Mireia Llaurado-Serra,Ignacio Martin-Loeches,Mohd Basri Mat Nor,Marlies Ostermann,Suzanne L. Parker,Jordi Rello,Darren M. Roberts,Michael S. Roberts,Michael S. Roberts,Brent Richards,Alejandro Rodríguez,Anka C Roehr,Claire Roger,Leonardo Seoane,Leonardo Seoane,Mahipal G. Sinnollareddy,Eduardo Sousa,Dolors Soy,Anna Spring,Therese Starr,Jane Thomas,John D. Turnidge,Steven C. Wallis,Tricia Williams,Tricia Williams,Xavier Wittebole,Xanthi T Zikou,Sanjoy K. Paul,Jeffrey Lipman,Jeffrey Lipman +70 more
TL;DR: In critically ill patients treated with RRT, antibiotic dosing regimens, RRT prescription and eTRCL varied markedly and resulted in highly variable antibiotic concentrations that failed to meet therapeutic targets in many patients.
Journal ArticleDOI
Using pharmacokinetics and pharmacodynamics to optimise dosing of antifungal agents in critically ill patients: a systematic review.
Mahipal G. Sinnollareddy,Sandra L. Peake,Michael S. Roberts,Jeffrey Lipman,Jeffrey Lipman,Jason A. Roberts +5 more
TL;DR: Based on the limited data available, dosing of some antifungal agents may have to be adjusted in critically ill patients with conserved renal function as well as in those requiring renal replacement therapy.
Journal ArticleDOI
In Vivo Microdialysis To Determine Subcutaneous Interstitial Fluid Penetration and Pharmacokinetics of Fluconazole in Intensive Care Unit Patients with Sepsis.
Mahipal G. Sinnollareddy,Michael S. Roberts,Jeffrey Lipman,Melissa Lassig-Smith,Therese Starr,Thomas Robertson,Sandra L. Peake,Jason A. Roberts,Jason A. Roberts +8 more
TL;DR: The data suggest that fluconazole was distributed variably, but incompletely, from plasma into subcutaneous interstitial fluid in this cohort of critically ill patients with sepsis.
Journal ArticleDOI
Pharmacokinetics of piperacillin in critically ill patients with acute kidney injury receiving sustained low-efficiency diafiltration.
Mahipal G. Sinnollareddy,Michael S. Roberts,Jeffrey Lipman,Jeffrey Lipman,Sandra L. Peake,Jason A. Roberts +5 more
TL;DR: Clearance, half-life and area under the concentration-time curve during SLED-f obtained from this study were comparable with those reported in the post-dilution mode of continuous veno-venous haemodiafiltration studies.