M
Makiko Kobayashi
Researcher at University of Texas Medical Branch
Publications - 122
Citations - 3302
Makiko Kobayashi is an academic researcher from University of Texas Medical Branch. The author has contributed to research in topics: T cell & Cytokine. The author has an hindex of 30, co-authored 114 publications receiving 3057 citations. Previous affiliations of Makiko Kobayashi include Tohoku Pharmaceutical University & Shriners Hospitals for Children - Galveston.
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Journal ArticleDOI
Three Different Neutrophil Subsets Exhibited in Mice with Different Susceptibilities to Infection by Methicillin-Resistant Staphylococcus aureus
Yasuhiro Tsuda,Hitoshi Takahashi,Makiko Kobayashi,Makiko Kobayashi,Toshiaki Hanafusa,David N. Herndon,Fujio Suzuki,Fujio Suzuki +7 more
TL;DR: It is shown that in addition to normal PMN (PMN-N), there are at least two distinct subsets of PMNs (PMn-I and PMN-II) distinguished as follows: cytokine and chemokine production and surface antigen expression.
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Glycyrrhizin, an active component of licorice roots, reduces morbidity and mortality of mice infected with lethal doses of influenza virus.
TL;DR: It is suggested that GR may protect mice exposed to a lethal amount of influenza virus through the stimulation of IFN-gamma production by T cells, because T cells have been shown to be producer cells of IF ngamma stimulated with the compound.
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CCL17 and IL-10 as Effectors That Enable Alternatively Activated Macrophages to Inhibit the Generation of Classically Activated Macrophages
Tatsushi Katakura,Masaru Miyazaki,Makiko Kobayashi,Makiko Kobayashi,David N. Herndon,Fujio Suzuki,Fujio Suzuki +6 more
TL;DR: Results indicate that CCL17 and IL-10 released from AAMφ inhibit CAMφ generation from RMφ stimulated with CpG DNA.
Journal Article
A Pathogenic Role of Th2 Cells and Their Cytokine Products on the Pulmonary Metastasis of Murine B16 Melanoma
TL;DR: The results suggest that the severity of pulmonary metastasis in mice receiving B16 melanoma cells is strongly influenced by the IL-4 released from tumor-associated Th2 cells.
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A protein associated with toll-like receptor 4 (PRAT4A) regulates cell surface expression of TLR4.
Yasutaka Wakabayashi,Makiko Kobayashi,Sachiko Akashi-Takamura,Natsuko Tanimura,Kazunori Konno,Koichiro Takahashi,Takashi Ishii,Taketoshi Mizutani,Hideo Iba,Taku Kouro,Satoshi Takaki,Kiyoshi Takatsu,Yoshiya Oda,Yasushi Ishihama,Shin-ichiroh Saitoh,Kensuke Miyake +15 more
TL;DR: It is shown here that PRAT4A, a novel protein associated with TLR4, regulates cell surface expression of TLR 4, and knockdown abolished LPS responsiveness in a cell line expressingTLR4/MD-2, probably due to the lack of cell surface TLR3.