M
Makoto Kuroda
Researcher at National Institutes of Health
Publications - 282
Citations - 14469
Makoto Kuroda is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Gene & Genome. The author has an hindex of 45, co-authored 262 publications receiving 12485 citations. Previous affiliations of Makoto Kuroda include Hokkaido University & University of Tsukuba.
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Journal ArticleDOI
Whole genome sequencing of meticillin-resistant Staphylococcus aureus
Makoto Kuroda,Toshiko Ohta,Ikuo Uchiyama,Tadashi Baba,Harumi Yuzawa,Ichizo Kobayashi,Longzhu Cui,Akio Oguchi,Ken-ichi Aoki,Yoshimi Nagai,JianQi Lian,Teruyo Ito,Mutsumi Kanamori,Hiroyuki Matsumaru,Atsushi Maruyama,Hiroyuki Murakami,Akira Hosoyama,Yoko Mizutani-Ui,Noriko K. Takahashi,Toshihiko Sawano,Ryu-ichi Inoue,Chikara Kaito,Kazuhisa Sekimizu,Hideki Hirakawa,Satoru Kuhara,Susumu Goto,Junko Yabuzaki,Minoru Kanehisa,Atsushi Yamashita,Kenshiro Oshima,Keiko Furuya,Chie Yoshino,Tadayoshi Shiba,Masahira Hattori,Naotake Ogasawara,Hideo Hayashi,Keiichi Hiramatsu +36 more
TL;DR: Investigation of many newly identified gene products, including the 70 putative virulence factors, will greatly improve the understanding of the biology of staphylococci and the processes of infectious diseases caused by S aureus.
Journal ArticleDOI
Genome and virulence determinants of high virulence community-acquired MRSA.
Tadashi Baba,Fumihiko Takeuchi,Makoto Kuroda,Harumi Yuzawa,Ken-ichi Aoki,Akio Oguchi,Yoshimi Nagai,Natsuko Iwama,Kazuyuki Asano,Timothy S. Naimi,Hiroko Kuroda,Longzhu Cui,Kenji Yamamoto,Keiichi Hiramatsu +13 more
TL;DR: The whole genome sequence of MW2, a strain of community-acquired MRSA, was ascertained by shotgun cloning and sequencing and found that it carried a range of virulence and resistance genes that was distinct from those displayed on the chromosomes of extant S aureus strains.
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Genetic Analysis of Human Norovirus Strains in Japan in 2016-2017.
Koo Nagasawa,Yuki Matsushima,Takumi Motoya,Fuminori Mizukoshi,Yo Ueki,Naomi Sakon,Koichi Murakami,Tomomi Shimizu,Nobuhiko Okabe,Noriko Nagata,Komei Shirabe,Hiroto Shinomiya,Wataru Suzuki,Makoto Kuroda,Tsuyoshi Sekizuka,Yoshiyuki Suzuki,Akihide Ryo,Kiyotaka Fujita,Kazunori Oishi,Kazuhiko Katayama,Hirokazu Kimura,Hirokazu Kimura +21 more
TL;DR: The time-scale phylogeny suggested that the common ancestors of the 2016 strains VP1 gene and RdRp region diverged in 2006 and 1999, respectively, and that the 2016 strain was the progeny of a pre-2016 GII.2.2 strains.
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Enhanced isolation of SARS-CoV-2 by TMPRSS2-expressing cells
Shutoku Matsuyama,Naganori Nao,Kazuya Shirato,Miyuki Kawase,Shinji Saito,Ikuyo Takayama,Noriyo Nagata,Tsuyoshi Sekizuka,Hiroshi Katoh,Fumihiro Kato,Masafumi Sakata,Maino Tahara,Satoshi Kutsuna,Norio Ohmagari,Makoto Kuroda,Tadaki Suzuki,Tsutomu Kageyama,Makoto Takeda +17 more
TL;DR: It is shown that a TMPRSS2-expressing VeroE6 cell line is highly susceptible to Sars-CoV-2 infection, making it useful for isolating and propagating SARS-Cov-2.
Journal ArticleDOI
The emergence and evolution of methicillin-resistant Staphylococcus aureus.
TL;DR: Recent epidemiological data imply that MRSA has embarked on another evolutionary path as a community pathogen, as at least one novel SCCmec element seems to have been successful in converting S. aureus strains from the normal human flora into MRSA.