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Journal ArticleDOI

Whole genome sequencing of meticillin-resistant Staphylococcus aureus

TLDR
Investigation of many newly identified gene products, including the 70 putative virulence factors, will greatly improve the understanding of the biology of staphylococci and the processes of infectious diseases caused by S aureus.
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This article is published in The Lancet.The article was published on 2001-04-21. It has received 2020 citations till now. The article focuses on the topics: GenBank & Whole genome sequencing.

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Structure, function and diversity of the healthy human microbiome

Curtis Huttenhower, +247 more
- 01 Jun 2012 - 
TL;DR: The Human Microbiome Project has analysed the largest cohort and set of distinct, clinically relevant body habitats so far, finding the diversity and abundance of each habitat’s signature microbes to vary widely even among healthy subjects, with strong niche specialization both within and among individuals.
Journal ArticleDOI

The role of nasal carriage in Staphylococcus aureus infections.

TL;DR: In this paper, the authors present an overview of the current knowledge of the determinants (both human and bacterial) and risks of S aureus nasal carriage, and summarise the population dynamics of SA.
Journal ArticleDOI

Phages and the Evolution of Bacterial Pathogens: from Genomic Rearrangements to Lysogenic Conversion

TL;DR: The current review presents the available genomics and biological data on prophages from bacterial pathogens in an evolutionary framework to demonstrate that the chromosomes from bacteria and their viruses (bacteriophages) are coevolving.
Journal ArticleDOI

Complete genome sequence of Lactobacillus plantarum WCFS1

TL;DR: The 3,308,274-bp sequence of the chromosome of Lactobacillus plantarum strain WCFS1, a single colony isolate of strain NCIMB8826 that was originally isolated from human saliva, has been determined, and contains 3,052 predicted protein-encoding genes, suggesting that these genes form a lifestyle adaptation region in the chromosome.
References
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Journal ArticleDOI

The Complete Genome Sequence of Escherichia coli K-12

TL;DR: The 4,639,221-base pair sequence of Escherichia coli K-12 is presented and reveals ubiquitous as well as narrowly distributed gene families; many families of similar genes within E. coli are also evident.
Journal ArticleDOI

The complete genome sequence of the Gram-positive bacterium Bacillus subtilis

F. Kunst, +154 more
- 20 Nov 1997 - 
TL;DR: Bacillus subtilis is the best-characterized member of the Gram-positive bacteria, indicating that bacteriophage infection has played an important evolutionary role in horizontal gene transfer, in particular in the propagation of bacterial pathogenesis.
Journal ArticleDOI

Genomic-sequence comparison of two unrelated isolates of the human gastric pathogen Helicobacter pylori

TL;DR: The overall genomic organization, gene order and predicted proteomes (sets of proteins encoded by the genomes) of the two strains are quite similar, and it is found that H. pylori was believed to exhibit a large degree of genomic and allelic diversity, but this is the first such genomic comparison.
Journal ArticleDOI

Exotoxins of Staphylococcus aureus

TL;DR: The molecular basis of PTSAg toxicity is presented in the context of two diseases known to be caused by these exotoxins: toxic shock syndrome and staphylococcal food poisoning.
Journal ArticleDOI

“Celbenin” - resistant Staphylococci

Robert Knox
- 14 Jan 1961 - 
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