M
Manfred Lindau
Researcher at Cornell University
Publications - 118
Citations - 7331
Manfred Lindau is an academic researcher from Cornell University. The author has contributed to research in topics: Exocytosis & Vesicle. The author has an hindex of 45, co-authored 114 publications receiving 6875 citations. Previous affiliations of Manfred Lindau include Max Planck Society & University of Seville.
Papers
More filters
Journal ArticleDOI
Patch-clamp techniques for time-resolved capacitance measurements in single cells.
Manfred Lindau,Erwin Neher +1 more
TL;DR: Two methods are described for estimation of passive cell parameters such as membrane capacitance, membrane conductance and access resistance in tight-seal whole cell recording by using a time domain technique and a lock-in amplifier.
Journal ArticleDOI
The exocytotic event in chromaffin cells revealed by patch amperometry
Almudena Albillos,Gregor Dernick,Heinz Horstmann,Wolfhard Almers,G. Alvarez de Toledo,Manfred Lindau +5 more
TL;DR: Exocytosis of individual chromaffin granules is investigated by using cell-attached capacitance measurements, combined with electrochemical detection of catecholamines, achieved by inserting a carbon-fibre electrode into the patch pipette and finding that the fusion-pore diameter stays at <3 nm for a variable period, which can last for several seconds, before it expands.
Journal ArticleDOI
High calcium concentrations shift the mode of exocytosis to the kiss-and-run mechanism.
TL;DR: In this paper, the authors investigate the fate of single secretory vesicles after fusion with the plasma membrane by measuring capacitance changes and transmitter release in rat chromaffin cells using the cell-attached patch-amperometry technique.
Journal ArticleDOI
Direct measurement of ion mobility in a conducting polymer.
Eleni Stavrinidou,Pierre Leleux,Harizo Rajaona,Dion Khodagholy,Jonathan Rivnay,Manfred Lindau,Sébastien Sanaur,George G. Malliaras +7 more
TL;DR: Using planar junctions between the conducting polymer PEDOT:PSS and various electrolytes, it is possible to inject common ions and directly observe their transit through the film and a straightforward estimate of the ion drift mobilities is estimated.
Journal ArticleDOI
Aspartic acid-96 is the internal proton donor in the reprotonation of the Schiff base of bacteriorhodopsin
TL;DR: Both the proton and azide effects, which are absent in wild type, indicate that the internal donor is removed and that the reprotonation pathway is different from wild type in these mutants.