M
Manfred Weidmann
Researcher at University of Stirling
Publications - 151
Citations - 6002
Manfred Weidmann is an academic researcher from University of Stirling. The author has contributed to research in topics: Recombinase Polymerase Amplification & Virus. The author has an hindex of 41, co-authored 141 publications receiving 5106 citations. Previous affiliations of Manfred Weidmann include University of Göttingen & University of Freiburg.
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Quantitative real-time PCR detection of Zika virus and evaluation with field-caught Mosquitoes
TL;DR: This assay is a useful tool for detection of ZIKV infection in regions where a number of other clinically indistinguishable arboviruses like dengue or chikungunya co-circulate.
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One-step RT-PCR for detection of Zika virus
Oumar Faye,Ousmane Faye,Anne Dupressoir,Anne Dupressoir,Manfred Weidmann,Mady Ndiaye,Amadou A. Sall +6 more
TL;DR: An RT-PCR assay targeting the envelope protein coding region is designed and evaluated for its specificity, detection limit, repeatability, and capacity to detect ZIKV isolates collected over a 40-year period from various African countries and hosts.
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Induction of MxA Gene Expression by Influenza A Virus Requires Type I or Type III Interferon Signaling
Dirk Holzinger,Carl Jorns,Silke Stertz,Stéphanie Boisson-Dupuis,Robert Thimme,Manfred Weidmann,Jean-Laurent Casanova,Otto Haller,Georg Kochs +8 more
TL;DR: MxA is a unique marker for the detection of type I and type III IFN activity during virus infections and IFN therapy, and cannot be triggered directly by virus infection.
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Transcription Analysis of the Genes tcdA‐E of the Pathogenicity Locus of Clostridium Difficile
Thomas Hundsberger,Veil Braun,Manfred Weidmann,Petra Leukel,Markus Sauerborn,Christoph von Eichel-Streiber +5 more
TL;DR: A model for the growth-phase-related, coordinate regulation of toxin expression wherein tcdC has a negative and tCDD a positive regulatory function on transcription of the tcdD,B,E and tcdA genes is discussed.
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A portable reverse transcription recombinase polymerase amplification assay for rapid detection of foot-and-mouth disease virus
Ahmed Abd El Wahed,Ayman H. El-Deeb,Mohamed El-Tholoth,Hanaa Abd El Kader,Abeer Ahmed,Sayed M. Hassan,Bernd Hoffmann,Bernd Haas,Mohamed A. Shalaby,Frank T. Hufert,Manfred Weidmann +10 more
TL;DR: FMDV RT-RPA was quicker and much easier to handle in the field than real-time RT-PCR and could be easily implemented to perform diagnostics at quarantine stations or farms for rapid spot-of-infection detection.