M
Manisha Desai
Researcher at Stanford University
Publications - 312
Citations - 18696
Manisha Desai is an academic researcher from Stanford University. The author has contributed to research in topics: Medicine & Population. The author has an hindex of 46, co-authored 276 publications receiving 15544 citations. Previous affiliations of Manisha Desai include University of California, Irvine & Columbia University Medical Center.
Papers
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Journal ArticleDOI
Obesity is associated with macrophage accumulation in adipose tissue
Stuart P. Weisberg,Daniel McCann,Manisha Desai,Michael Rosenbaum,Rudolph L. Leibel,Anthony W. Ferrante +5 more
TL;DR: Transcript expression in perigonadal adipose tissue from groups of mice in which adiposity varied due to sex, diet, and the obesity-related mutations agouti (Ay) and obese (Lepob) found that the expression of 1,304 transcripts correlated significantly with body mass.
Journal ArticleDOI
Large-Scale Assessment of a Smartwatch to Identify Atrial Fibrillation
Marco V Perez,Kenneth W. Mahaffey,Haley Hedlin,John S. Rumsfeld,Ariadna Garcia,Todd A. Ferris,Vidhya Balasubramanian,Andrea M. Russo,Amol Rajmane,Lauren Cheung,Grace Hung,Justin Lee,Peter R. Kowey,Nisha Talati,Divya Nag,Santosh Gummidipundi,Alexis L. Beatty,Mellanie True Hills,Sumbul A Desai,Christopher B. Granger,Manisha Desai,Mintu P. Turakhia,Apple Heart Study Investigators +22 more
TL;DR: This siteless study design provides a foundation for large-scale pragmatic studies in which outcomes or adherence can be reliably assessed with user-owned devices and the probability of receiving an irregular pulse notification was low.
Journal ArticleDOI
Genetic and environmental determinants of human NK cell diversity revealed by mass cytometry
Amir Horowitz,Dara M. Strauss-Albee,Michael D. Leipold,Jessica Kubo,Neda Nemat-Gorgani,Ozge C. Dogan,Cornelia L. Dekker,Sally Mackey,Holden T. Maecker,Gary E. Swan,Mark M. Davis,Paul Norman,Lisbeth A. Guethlein,Manisha Desai,Peter Parham,Catherine A. Blish +15 more
TL;DR: The data suggest that inhibitory receptors may contribute more to NK cell self-tolerance, whereas activating receptors may guide response to pathogens and tumors, and the possibility that discrete NK cell subpopulations could be harnessed for immunotherapeutic strategies in the settings of infection, reproduction, and transplantation.
Journal ArticleDOI
Effect of Low-Fat vs Low-Carbohydrate Diet on 12-Month Weight Loss in Overweight Adults and the Association With Genotype Pattern or Insulin Secretion: The DIETFITS Randomized Clinical Trial.
Christopher D. Gardner,John F. Trepanowski,Liana C Del Gobbo,Michelle E Hauser,Joseph Rigdon,John P. A. Ioannidis,Manisha Desai,Abby C. King +7 more
TL;DR: There was no significant difference in weight change between a healthy low-fat diet vs ahealthy low-carbohydrate diet, and neither genotype pattern nor baseline insulin secretion was associated with the dietary effects on weight loss in this 12-month weight loss study.
Journal ArticleDOI
Rationale and design of a large-scale, app-based study to identify cardiac arrhythmias using a smartwatch: The Apple Heart Study.
Mintu P. Turakhia,Mintu P. Turakhia,Manisha Desai,Haley Hedlin,Amol Rajmane,Nisha Talati,Todd A. Ferris,Sumbul A Desai,Divya Nag,Mithun Patel,Peter R. Kowey,John S. Rumsfeld,Andrea M. Russo,Mellanie True Hills,Christopher B. Granger,Kenneth W. Mahaffey,Marco V Perez +16 more
TL;DR: The results of this trial will provide initial evidence for the ability of a smartwatch algorithm to identify pulse irregularity and variability which may reflect previously unknown AF.