M
Michael Rosenbaum
Researcher at Columbia University
Publications - 123
Citations - 23454
Michael Rosenbaum is an academic researcher from Columbia University. The author has contributed to research in topics: Weight loss & Leptin. The author has an hindex of 48, co-authored 109 publications receiving 21031 citations. Previous affiliations of Michael Rosenbaum include Rockefeller University & Tufts University.
Papers
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Journal ArticleDOI
Obesity is associated with macrophage accumulation in adipose tissue
Stuart P. Weisberg,Daniel McCann,Manisha Desai,Michael Rosenbaum,Rudolph L. Leibel,Anthony W. Ferrante +5 more
TL;DR: Transcript expression in perigonadal adipose tissue from groups of mice in which adiposity varied due to sex, diet, and the obesity-related mutations agouti (Ay) and obese (Lepob) found that the expression of 1,304 transcripts correlated significantly with body mass.
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Changes in Energy Expenditure Resulting from Altered Body Weight
TL;DR: Maintenance of a reduced or elevated body weight is associated with compensatory changes in energy expenditure, which oppose the maintenance of a body weight that is different from the usual weight, which may account for the poor long-term efficacy of treatments for obesity.
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The Long-Term Stability of the Human Gut Microbiota
Jeremiah J. Faith,Janaki L. Guruge,Mark R. Charbonneau,Sathish Subramanian,Henning Seedorf,Andrew L. Goodman,Jose C. Clemente,Rob Knight,Rob Knight,Andrew C. Heath,Rudolph L. Leibel,Michael Rosenbaum,Jeffrey I. Gordon +12 more
TL;DR: Low-error sequencing data suggest that initial microbial colonizers of infant guts could persist over the life span of an individual, and members of Bacteroidetes and Actinobacteria are significantly more stable components than the population average.
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Effects of gender, body composition, and menopause on plasma concentrations of leptin.
Michael Rosenbaum,M Nicolson,Jules Hirsch,Steven B. Heymsfield,Dympna Gallagher,Florence Chu,Rudolph L. Leibel +6 more
TL;DR: While plasma [leptin], corrected for FM, declines significantly in women post-menopause, this decline is not sufficient to account for the striking sexual dimorphism in the relationship of leptin to fat mass.
Journal ArticleDOI
Brown Remodeling of White Adipose Tissue by SirT1-Dependent Deacetylation of Pparγ
Li Qiang,Liheng Wang,Ning Kon,Wenhui Zhao,Sangkyu Lee,Yiying Zhang,Michael Rosenbaum,Yingming Zhao,Wei Gu,Stephen R. Farmer,Domenico Accili +10 more
TL;DR: It is proposed that SirT1-dependent P parγ deacetylation is a form of selective Pparγ modulation of potential therapeutic import in order to staunch the current obesity epidemic.