M
Manuel Palacín
Researcher at University of Barcelona
Publications - 243
Citations - 18971
Manuel Palacín is an academic researcher from University of Barcelona. The author has contributed to research in topics: Amino acid & Skeletal muscle. The author has an hindex of 67, co-authored 235 publications receiving 17265 citations. Previous affiliations of Manuel Palacín include Carlos III Health Institute & Casa Sollievo della Sofferenza.
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Journal ArticleDOI
Mitochondrial Dynamics in Mammalian Health and Disease
TL;DR: Findings in the field of mitochondrial dynamics in mammalian cells and their implication in human pathologies have established mitochondrial dynamics as a consolidated area in cellular physiology.
Journal ArticleDOI
Molecular Biology of Mammalian Plasma Membrane Amino Acid Transporters
TL;DR: The tissue expression, transport characteristics, structure-function relationship, and the putative physiological roles of four amino acid transporters belonging to four protein families are described.
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Mitofusin-2 Determines Mitochondrial Network Architecture and Mitochondrial Metabolism A NOVEL REGULATORY MECHANISM ALTERED IN OBESITY
Daniel Bach,Sara Pich,Francesc X. Soriano,Nathalie Vega,Bernhard Baumgartner,Josep Oriola,Jens R. Daugaard,Jorge Lloberas,Marta Camps,Juleen R. Zierath,Rémi Rabasa-Lhoret,Harriet Wallberg-Henriksson,Martine Laville,Manuel Palacín,Hubert Vidal,Francisca Rivera,Martin D. Brand,Antonio Zorzano +17 more
TL;DR: It is shown that Mfn2 (mitofusin 2), a mitochondrial membrane protein that participates in mitochondrial fusion in mammalian cells, is induced during myogenesis and contributes to the maintenance and operation of the mitochondrial network.
Journal ArticleDOI
CATs and HATs: the SLC7 family of amino acid transporters
François Verrey,Ellen I. Closs,Carsten A. Wagner,Manuel Palacín,Hitoshi Endou,Yoshikatsu Kanai +5 more
TL;DR: Members of the CAT family transport essentially cationic amino acids by facilitated diffusion with differential trans-stimulation by intracellular substrates and may regulate the rate of NO synthesis by controlling the uptake of l-arginine as the substrate for nitric oxide synthase (NOS).
Journal ArticleDOI
Mitofusin 2 (Mfn2) links mitochondrial and endoplasmic reticulum function with insulin signaling and is essential for normal glucose homeostasis
David Sebastián,María Isabel Hernández-Alvarez,Jessica Segalés,Eleonora Sorianello,Juan Pablo Muñoz,David Sala,Aurélie Waget,Marc Liesa,José C. Paz,Peddinti Gopalacharyulu,Matej Orešič,Sara Pich,Rémy Burcelin,Manuel Palacín,Antonio Zorzano +14 more
TL;DR: This study provides an important description of a unique unexpected role of Mfn2 coordinating mitochondria and endoplasmic reticulum function, leading to modulation of insulin signaling and glucose homeostasis in vivo.