M
Marc-Henri Stern
Researcher at Curie Institute
Publications - 196
Citations - 12240
Marc-Henri Stern is an academic researcher from Curie Institute. The author has contributed to research in topics: Gene & Breast cancer. The author has an hindex of 49, co-authored 168 publications receiving 9402 citations. Previous affiliations of Marc-Henri Stern include Necker-Enfants Malades Hospital & French Institute of Health and Medical Research.
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Journal ArticleDOI
The TCL1 oncoprotein inhibits activation-induced cell death by impairing PKCθ and ERK pathways
Gilles Despouy,Gilles Despouy,Marjorie Joiner,Marjorie Joiner,Emilie Le Toriellec,Emilie Le Toriellec,Robert Weil,Marc-Henri Stern,Marc-Henri Stern +8 more
TL;DR: Investigation of the biologic functions of TCL1 in the T-cell lineage using various cell lines, and primary malignant and normal lymphocytes shows that TCL 1 inhibits AICD in T cells by blocking PKCtheta and ERK activation, upon cellular activation.
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The biological and prognostic significance of angiotropism in uveal melanoma.
Raymond L. Barnhill,Raymond L. Barnhill,Mengliang Ye,Aude Batistella,Marc-Henri Stern,Sergio Roman-Roman,Rémi Dendale,Olivier Lantz,Sophie Piperno-Neumann,Laurence Desjardins,Nathalie Cassoux,Nathalie Cassoux,Claire Lugassy +12 more
TL;DR: Angiotropism and monosomy 3 were independent prognostic factors for both metastases and death in UM, however, irrespective of any prognostic value, the true importance of angiotropist is its biological significance as a marker of an alternative metastatic pathway.
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ShallowHRD: detection of homologous recombination deficiency from shallow whole genome sequencing.
Alexandre Eeckhoutte,Alexandre Eeckhoutte,Alexandre Houy,Alexandre Houy,Elodie Manié,Elodie Manié,Manon Reverdy,Manon Reverdy,Ivan Bièche,Elisabetta Marangoni,Oumou Goundiam,Anne Vincent-Salomon,Dominique Stoppa-Lyonnet,Dominique Stoppa-Lyonnet,François-Clément Bidard,François-Clément Bidard,Marc-Henri Stern,Marc-Henri Stern,Tatiana Popova,Tatiana Popova +19 more
TL;DR: ShallowHRD displays efficiency comparable to most state-of-art approaches, is cost-effective, generates low-storable outputs and is also suitable for fixed-formalin paraffin embedded tissues.
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Solution structure of the recombinant human oncoprotein p13MTCP1.
Yinshan Yang,Laurent Guignard,André Padilla,François Hoh,Marie-Paule Strub,Marc-Henri Stern,Jean-Marc Lhoste,Christian Roumestand +7 more
TL;DR: The three-dimensional solution structure of the recombinant p13MTCP1 determined by homonuclear proton two-dimensional NMR methods at 600 MHz consists of an orthogonal β-barrel, composed of eight antiparallel β-strands which present an original arrangement.
Journal ArticleDOI
Association of Partial Chromosome 3 Deletion in Uveal Melanomas With Metastasis-Free Survival.
Manuel Rodrigues,Ait Rais K,Salviat F,Algret N,Simaga F,Raymond L. Barnhill,Sophie Gardrat,Servois,Pascale Mariani,Sophie Piperno-Neumann,Sergio Roman-Roman,Olivier Delattre,Nathalie Cassoux,Alexia Savignoni,Marc-Henri Stern,Gaëlle Pierron +15 more
TL;DR: Findings suggest that partial deletion of chromosome 3 encompassing the BAP1 locus is associated with poor prognosis, and a cytogenetic classification of UMs could be proposed based on the status of the BAPD locus instead of the chromosome 3 locus, while also taking chromosome 8q into account.