M
Marc-Henri Stern
Researcher at Curie Institute
Publications - 196
Citations - 12240
Marc-Henri Stern is an academic researcher from Curie Institute. The author has contributed to research in topics: Gene & Breast cancer. The author has an hindex of 49, co-authored 168 publications receiving 9402 citations. Previous affiliations of Marc-Henri Stern include Necker-Enfants Malades Hospital & French Institute of Health and Medical Research.
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Journal ArticleDOI
Genetic landscape of uveal melanoma.
TL;DR: There is a major clinical need for drugs targeting either the downstream pathways of Gαq and Gα11 or the biological cell functions dysregulated by BAP1 loss of function.
Journal ArticleDOI
Real-Time Detection of ESR1 Mutation in Blood by Droplet Digital PCR in the PADA-1 Trial: Feasibility and Cross-Validation with NGS.
Céline Callens,François-Clément Bidard,Anais Curto-Taribo,O. Trabelsi-Grati,Samia Melaabi,Suzette Delaloge,Anne-Claire Hardy-Bessard,Thomas Bachelot,Florian Clatot,Thibault De La Motte Rouge,Jean-Luc Canon,Laurent Arnould,Fabrice Andre,Sandrine Marques,Marc-Henri Stern,Jean-Yves Pierga,Anne Vincent-Salomon,Camille Benoist,Emmanuelle Jeannot,Frédérique Berger,Ivan Bièche,Anne Pradines +21 more
TL;DR: These results from a large-scale trial support the feasibility and accuracy of real-time bESR1mut tracking by ddPCR, opening new opportunities for therapeutic interventions.
Journal ArticleDOI
Epigenetically controlled tumor antigens derived from splice junctions between exons and transposable elements
Marianne Burbage,Ares Rocanin-Arjo,Blandine Baudon,YA Arribas,Antonela Merlotti,Derek C Rookhuizen,Sandrine Heurtebise-Chrétien,Mengliang Ye,Alexandre Houy,Nina Burgdorf,Guadalupe Suarez,Marine Gros,Benjamin Sadacca,Montserrat Carrascal,Andrea Garmilla,Mylène Bohec,Sylvain Baulande,Bérangère Lombard,Damarys Loew,Joshua J. Waterfall,Marc-Henri Stern,Christel Goudot,Sebastian Amigorena +22 more
TL;DR: In this article , the authors explore the possibility that noncanonical splice junctions between exons and transposable elements represent a source of tumor-specific antigens.
Journal ArticleDOI
Functional subdivision of HLA-DRw8 with influenza-specific cloned cell lines
Yvette Henin,G Sterkers,Elisabeth Gomard,L. Gebuhrer,A. C. Freidel,Virginia Lepage,Marc-Henri Stern,Jean Michon,H. Betuel,Jean-Paul Levy +9 more
TL;DR: The objective of the study was to establish a baseline for the estimation of the prophylactic needs of the immune system in the context of organ transplantation Humaine.
Posted ContentDOI
Deep Learning identifies new morphological patterns of Homologous Recombination Deficiency in luminal breast cancers from whole slide images
Tristan Lazard,Tristan Lazard,Tristan Lazard,Guillaume Bataillon,Guillaume Bataillon,Peter Naylor,Peter Naylor,Peter Naylor,Tatiana Popova,François-Clément Bidard,François-Clément Bidard,Dominique Stoppa-Lyonnet,Marc-Henri Stern,Etienne Decencière,Thomas Walter,Thomas Walter,Thomas Walter,Anne Vincent Salomon,Anne Vincent Salomon +18 more
TL;DR: In this paper, a deep learning model was used to predict homologous recombination DNA-repair deficiency (HRD) in a controlled cohort with unprecedented accuracy (AUC: 0.86) and a new visualization technique was developed to automatically extract new morphological features related to HRD.