M
Marcelo B. P. Amato
Researcher at University of São Paulo
Publications - 195
Citations - 17045
Marcelo B. P. Amato is an academic researcher from University of São Paulo. The author has contributed to research in topics: Mechanical ventilation & ARDS. The author has an hindex of 49, co-authored 172 publications receiving 13827 citations. Previous affiliations of Marcelo B. P. Amato include Federal University of Rio de Janeiro.
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Journal ArticleDOI
Effect of a Protective-Ventilation Strategy on Mortality in the Acute Respiratory Distress Syndrome
Marcelo B. P. Amato,Carmen Silvia Valente Barbas,D Medeiros,R B Magaldi,Guilherme Schettino,Geraldo Lorenzi-Filho,Ronaldo Adib Kairalla,Daniel Deheinzelin,Carlos Munoz,Roselaine Pinheiro de Oliveira,Teresa Yae Takagaki,Carlos Roberto Ribeiro de Carvalho +11 more
TL;DR: As compared with conventional ventilation, the protective strategy was associated with improved survival at 28 days, a higher rate of weaning from mechanical ventilation, and a lower rate of barotrauma in patients with the acute respiratory distress syndrome.
Journal ArticleDOI
Driving Pressure and Survival in the Acute Respiratory Distress Syndrome
Marcelo B. P. Amato,Maureen O. Meade,Arthur S. Slutsky,Laurent J. Brochard,Eduardo L. V. Costa,David A. Schoenfeld,Thomas E. Stewart,Matthias Briel,Matthias Briel,Daniel Talmor,Alain Mercat,Jean-Christophe Richard,Carlos Roberto Ribeiro de Carvalho,Roy G. Brower +13 more
TL;DR: It is found that ΔP was the ventilation variable that best stratified risk and decreases in ΔP owing to changes in ventilator settings were strongly associated with increased survival.
Journal ArticleDOI
An Official American Thoracic Society/European Society of Intensive Care Medicine/Society of Critical Care Medicine Clinical Practice Guideline: Mechanical Ventilation in Adult Patients with Acute Respiratory Distress Syndrome
Eddy Fan,Lorenzo Del Sorbo,Ewan C. Goligher,Carol L. Hodgson,Laveena Munshi,Allan J. Walkey,Neill K. J. Adhikari,Marcelo B. P. Amato,Richard D. Branson,Roy G. Brower,Niall D. Ferguson,Ognjen Gajic,Luciano Gattinoni,Dean R. Hess,Jordi Mancebo,Maureen O. Meade,Daniel F. McAuley,Antonio Pesenti,V. Marco Ranieri,Gordon D. Rubenfeld,Eileen Rubin,Maureen A. Seckel,Arthur S. Slutsky,Daniel Talmor,B. Taylor Thompson,Hannah Wunsch,Elizabeth Uleryk,Jan Brozek,Laurent Brochard +28 more
TL;DR: Clinicians managing patients with ARDS should personalize decisions for their patients, particularly regarding the conditional recommendations in this guideline, which is strong for mechanical ventilation using lower tidal volumes and lower inspiratory pressures.
Journal ArticleDOI
Effect of Lung Recruitment and Titrated Positive End-Expiratory Pressure (PEEP) vs Low PEEP on Mortality in Patients With Acute Respiratory Distress Syndrome A Randomized Clinical Trial
Alexandre Biasi Cavalcanti,Erica Aranha Suzumura,Lígia Nasi Laranjeira,Denise M. Paisani,Lucas P. Damiani,Hélio Penna Guimarães,Edson Romano,Marisa de Moraes Regenga,Luzia Noriko Takahashi Taniguchi,Cassiano Teixeira,Roselaine Pinheiro de Oliveira,Flávia Ribeiro Machado,Fredi Alexander Diaz-Quijano,Meton Soares de Alencar Filho,Israel Silva Maia,Eliana Bernardete Caser,Wilson de Oliveira Filho,Marcos C. Borges,Priscilla de Aquino Martins,Mirna Matsui,Gustavo A. Ospina-Tascón,Thiago Simões Giancursi,Nelson Dario Giraldo-Ramirez,Silvia Regina Rios Vieira,Maria da Graça Pasquotto de Lima Assef,Mohd Shahnaz Hasan,Wojciech Szczeklik,Fernando Rios,Marcelo B. P. Amato,Otavio Berwanger,Carlos Roberto Ribeiro de Carvalho +30 more
TL;DR: In patients with moderate to severe ARDS, a strategy with lung recruitment and titrated PEEP compared with low PEEP increased 28-day all-cause mortality, and these findings do not support the routine use of lung recruitment maneuver and PEEP titration in these patients.
Journal ArticleDOI
Beneficial effects of the open lung approach with low distending pressures in acute respiratory distress syndrome : a prospective randomized study on mechanical ventilation
Marcelo B. P. Amato,C S Barbas,D Medeiros,G de P Schettino,G Lorenzi Filho,Ronaldo Adib Kairalla,Daniel Deheinzelin,Claudia Morais,E de O Fernandes,T Y Takagaki +9 more
TL;DR: It is concluded that the NA ventilatory strategy can markedly improve the lung function in patients with ARDS, increasing the chances of early weaning and lung recovery during mechanical ventilation.