M
Marcelo B. Soares
Researcher at Northwestern University
Publications - 119
Citations - 10492
Marcelo B. Soares is an academic researcher from Northwestern University. The author has contributed to research in topics: Expressed sequence tag & Gene. The author has an hindex of 50, co-authored 119 publications receiving 10097 citations. Previous affiliations of Marcelo B. Soares include Children's Memorial Hospital & University of York.
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Journal ArticleDOI
The I.M.A.G.E. Consortium: an integrated molecular analysis of genomes and their expression.
TL;DR: An effort to share resources such that the maximum amount of gene-related data is obtained with the last redundancy is described, to have the data derived from the use of common reagents placed in public databases, and to create master arrays containing a representative cDNA clone from each gene.
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Genome sequence of Aedes aegypti, a major arbovirus vector
Vishvanath Nene,Jennifer R. Wortman,Daniel Lawson,Brian J. Haas,Chinnappa D. Kodira,Zhijian Jake Tu,Brendan J. Loftus,Zhiyong Xi,Karyn Megy,Manfred Grabherr,Quinghu Ren,Evgeny M. Zdobnov,Neil F. Lobo,Kathryn S. Campbell,Susan E. Brown,Maria de Fatima Bonaldo,Jingsong Zhu,Steven P. Sinkins,David G. Hogenkamp,Paolo Amedeo,Peter Arensburger,Peter W. Atkinson,Shelby L. Bidwell,Jim Biedler,Ewan Birney,Robert V. Bruggner,Javier Costas,Monique R. Coy,Jonathan Crabtree,Matt Crawford,Becky deBruyn,David DeCaprio,Karin Eiglmeier,Eric Eisenstadt,Hamza El-Dorry,William M. Gelbart,Suely Lopes Gomes,Martin Hammond,Linda Hannick,James R. Hogan,Michael H. Holmes,David M. Jaffe,J. Spencer Johnston,Ryan C. Kennedy,Hean Koo,Saul A. Kravitz,Evgenia V. Kriventseva,David Kulp,Kurt LaButti,Eduardo Lee,Song Li,Diane D. Lovin,Chunhong Mao,Evan Mauceli,Carlos Frederico Martins Menck,Jason R. Miller,Philip Montgomery,Akio Mori,Ana L. T. O. Nascimento,Horacio Naveira,Chad Nusbaum,Sinéad B. O'Leary,Joshua Orvis,Mihaela Pertea,Hadi Quesneville,Kyanne R. Reidenbach,Yu-Hui Rogers,Charles Roth,Jennifer R. Schneider,Michael C. Schatz,Martin Shumway,Mario Stanke,Eric O. Stinson,Jose M. C. Tubio,Janice P. Vanzee,Sergio Verjovski-Almeida,Doreen Werner,Owen White,Stefan Wyder,Qiandong Zeng,Qi Zhao,Yongmei Zhao,Catherine A. Hill,Alexander S. Raikhel,Marcelo B. Soares,Dennis L. Knudson,Norman H. Lee,James E. Galagan,Steven L. Salzberg,Ian T. Paulsen,George Dimopoulos,Frank H. Collins,Bruce W. Birren,Claire M. Fraser-Liggett,David W. Severson +94 more
TL;DR: A draft sequence of the genome of Aedes aegypti, the primary vector for yellow fever and dengue fever, which at approximately 1376 million base pairs is about 5 times the size of the genomes of the malaria vector Anopheles gambiae was presented in this paper.
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Normalization and subtraction: two approaches to facilitate gene discovery.
TL;DR: A subtractive hybridization approach designed specifically to eliminate (or reduce significantly the representation of) large pools of arrayed and (mostly) sequenced clones from normalized libraries yet to be (or just partly) surveyed is developed.
Journal ArticleDOI
Construction and characterization of a normalized cDNA library
Marcelo B. Soares,Maria de Fatima Bonaldo,Pierre Jelene,Long Su,L Lawton,Argiris Efstratiadis +5 more
TL;DR: An evaluation of the extent of normalization has indicated that, from an extreme range of abundance in the original library, the frequency of occurrence of any clone examined in the normalized library was brought within the narrow range of only 1 order of magnitude.
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Rapid cDNA sequencing (expressed sequence tags) from a directionally cloned human infant brain cDNA library
TL;DR: A human infant brain cDNA library, made specifically for production of expressed sequence tags (ESTs) was evaluated by partial sequencing of over 1,600 clones, and two proteins similar to the Alzheimer's disease amyloid precursor protein were identified.