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Alexander S. Raikhel
Researcher at University of California, Riverside
Publications - 153
Citations - 13017
Alexander S. Raikhel is an academic researcher from University of California, Riverside. The author has contributed to research in topics: Aedes aegypti & Vitellogenesis. The author has an hindex of 63, co-authored 150 publications receiving 11822 citations. Previous affiliations of Alexander S. Raikhel include Michigan State University.
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Journal ArticleDOI
Genome sequence of Aedes aegypti, a major arbovirus vector
Vishvanath Nene,Jennifer R. Wortman,Daniel Lawson,Brian J. Haas,Chinnappa D. Kodira,Zhijian Jake Tu,Brendan J. Loftus,Zhiyong Xi,Karyn Megy,Manfred Grabherr,Quinghu Ren,Evgeny M. Zdobnov,Neil F. Lobo,Kathryn S. Campbell,Susan E. Brown,Maria de Fatima Bonaldo,Jingsong Zhu,Steven P. Sinkins,David G. Hogenkamp,Paolo Amedeo,Peter Arensburger,Peter W. Atkinson,Shelby L. Bidwell,Jim Biedler,Ewan Birney,Robert V. Bruggner,Javier Costas,Monique R. Coy,Jonathan Crabtree,Matt Crawford,Becky deBruyn,David DeCaprio,Karin Eiglmeier,Eric Eisenstadt,Hamza El-Dorry,William M. Gelbart,Suely Lopes Gomes,Martin Hammond,Linda Hannick,James R. Hogan,Michael H. Holmes,David M. Jaffe,J. Spencer Johnston,Ryan C. Kennedy,Hean Koo,Saul A. Kravitz,Evgenia V. Kriventseva,David Kulp,Kurt LaButti,Eduardo Lee,Song Li,Diane D. Lovin,Chunhong Mao,Evan Mauceli,Carlos Frederico Martins Menck,Jason R. Miller,Philip Montgomery,Akio Mori,Ana L. T. O. Nascimento,Horacio Naveira,Chad Nusbaum,Sinéad B. O'Leary,Joshua Orvis,Mihaela Pertea,Hadi Quesneville,Kyanne R. Reidenbach,Yu-Hui Rogers,Charles Roth,Jennifer R. Schneider,Michael C. Schatz,Martin Shumway,Mario Stanke,Eric O. Stinson,Jose M. C. Tubio,Janice P. Vanzee,Sergio Verjovski-Almeida,Doreen Werner,Owen White,Stefan Wyder,Qiandong Zeng,Qi Zhao,Yongmei Zhao,Catherine A. Hill,Alexander S. Raikhel,Marcelo B. Soares,Dennis L. Knudson,Norman H. Lee,James E. Galagan,Steven L. Salzberg,Ian T. Paulsen,George Dimopoulos,Frank H. Collins,Bruce W. Birren,Claire M. Fraser-Liggett,David W. Severson +94 more
TL;DR: A draft sequence of the genome of Aedes aegypti, the primary vector for yellow fever and dengue fever, which at approximately 1376 million base pairs is about 5 times the size of the genomes of the malaria vector Anopheles gambiae was presented in this paper.
Journal ArticleDOI
Accumulation of yolk proteins in insect oocytes
TL;DR: In insects, accumulation of yolk, or vitellogenesis, is a heterosynthetic pro cess, in which an extraovarian tissue, the fat body, produces yolk protein precursors, and the role of endocytosis in yolk deposition in insect oocytes is implicated.
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Evolutionary Dynamics of Immune-Related Genes and Pathways in Disease-Vector Mosquitoes
Robert M. Waterhouse,Evgenia V. Kriventseva,Stephan Meister,Zhiyong Xi,Kanwal S. Alvarez,Lyric C. Bartholomay,Carolina Barillas-Mury,Guowu Bian,Stéphanie Blandin,Bruce M. Christensen,Yuemei Dong,Haobo Jiang,Michael R. Kanost,Anastasios C. Koutsos,Elena A. Levashina,Jianyong Li,Petros Ligoxygakis,Robert M. MacCallum,George F. Mayhew,António M. Mendes,Kristin Michel,Mike A. Osta,Susan M. Paskewitz,Sang Woon Shin,Dina Vlachou,Lihui Wang,Weiqi Wei,Liangbiao Zheng,Zhen Zou,David W. Severson,Alexander S. Raikhel,Fotis C. Kafatos,George Dimopoulos,Evgeny M. Zdobnov,George K. Christophides +34 more
TL;DR: Analysis of immune signaling pathways and response modules reveals both conservative and rapidly evolving features associated with different functional gene categories and particular aspects of immune reactions, suggesting how innate immunity may have evolved.
Journal ArticleDOI
Wolbachia induces reactive oxygen species (ROS)-dependent activation of the Toll pathway to control dengue virus in the mosquito Aedes aegypti
TL;DR: The results indicate that a symbiotic bacterium can manipulate the host defense system to facilitate its own persistent infection, resulting in a compromise of the mosquito's ability to host human pathogens.
Journal ArticleDOI
Molecular characteristics of insect vitellogenins and vitellogenin receptors
TL;DR: Though vertebrate VgRs, insect VgR/YPRs, and LDLR-related proteins/megalins all accommodate one cluster of eight Class A repeats, fingerprint analysis of the repeats in these clusters indicate they are not directly homologous with one another, but have undergone differing histories of duplications, deletions, and exon shuffling so that their apparent similarity is superficial.