M
Marco Lucchi
Researcher at University of Pisa
Publications - 225
Citations - 11205
Marco Lucchi is an academic researcher from University of Pisa. The author has contributed to research in topics: Lung cancer & Cancer. The author has an hindex of 47, co-authored 199 publications receiving 9227 citations.
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Journal ArticleDOI
A common polymorphism within MSLN affects miR-611 binding site and soluble mesothelin levels in healthy people.
Sonia Garritano,Chiara De Santi,Roberto Silvestri,Ombretta Melaiu,Monica Cipollini,Elisa Barone,Marco Lucchi,Roberto Barale,Luciano Mutti,Federica Gemignani,Alessandra Bonotti,Rudy Foddis,Alfonso Cristaudo,Stefano Landi +13 more
TL;DR: SMRP performance as diagnostic biomarker improved by considering the genotype rs1057147, which most likely affects a binding site for miR-611, and among non-MPM volunteers, GG homozygotes have the lowest SMRP levels.
Journal ArticleDOI
Gene-Specific Methylation Analysis in Thymomas of Patients with Myasthenia Gravis
Angela Lopomo,Roberta Ricciardi,Michelangelo Maestri,Anna De Rosa,Franca Melfi,Marco Lucchi,Alfredo Mussi,Fabio Coppedè,Lucia Migliore +8 more
TL;DR: The present study suggests that MTHFR methylation is increased in thymomas obtained from MG patients; furthermore, some degrees of methylation of the DNMT3A gene were observed inThymic tissue with respect to blood.
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Applications of tissue microarray technology in immunohistochemistry: a study on c-kit expression in small cell lung cancer.
Valentina Donati,Pinuccia Faviana,Matteo Dell'Omodarme,Maria Cristina Prati,Tiziano Camacci,Katia De Ieso,Riccardo Giannini,Marco Lucchi,Alfredo Mussi,Raffaele Pingitore,Fulvio Basolo,Gabriella Fontanini +11 more
TL;DR: Tissue microarray technology cannot be a substitute for whole sections in clinical diagnosis of individual cases, and shows a rather poor sensitivity and correlation in the present study.
Journal ArticleDOI
A strategy for thoracoscopic resection of small pulmonary nodules
Marcello Carlo Ambrogi,Paolo Dini,Giuseppe Boni,F Melfi,Marco Lucchi,Olivia Fanucchi,Giuliano Mariani,Alfredo Mussi +7 more
TL;DR: Correct patient selection may limit this necessity for thoracoscopic resection of small pulmonary nodules, without an increased conversion rate to thoracotomy, if endothoracic ultrasonography is available.
Journal ArticleDOI
EGFR and KRAS mutational analysis in a large series of Italian non-small cell lung cancer patients: 2,387 cases from a single center
Riccardo Giannini,Cristiana Lupi,Elisa Sensi,Greta Alì,Agnese Proietti,Laura Boldrini,Adele Servadio,Mirella Giordano,Elisabetta Macerola,Rossella Bruno,Nicla Borrelli,Antonio Chella,Franca Melfi,Marco Lucchi,Alessandro Ribechini,Enrico Vasile,Federico Cappuzzo,Alfredo Mussi,Gabriella Fontanini +18 more
TL;DR: The results confirm that small biopsy or cytological samples can be used for reliable EGFR and KRAS mutation testing and indicate that adopting the MALDI‑TOF platform reduces the rate of missed samples among the samples.