M
Marcus Schuchmann
Researcher at University of Mainz
Publications - 77
Citations - 6778
Marcus Schuchmann is an academic researcher from University of Mainz. The author has contributed to research in topics: Apoptosis & Programmed cell death. The author has an hindex of 35, co-authored 75 publications receiving 6283 citations. Previous affiliations of Marcus Schuchmann include Weizmann Institute of Science.
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Journal ArticleDOI
Prospective randomized study of doxorubicin-eluting-bead embolization in the treatment of hepatocellular carcinoma: results of the PRECISION V study
Johannes Lammer,K. Malagari,Thomas J. Vogl,Frank Pilleul,Alban Denys,A. Watkinson,Michael B. Pitton,Géraldine Sergent,Thomas Pfammatter,Sylvain Terraz,Yves Benhamou,Yves Avajon,Thomas Gruenberger,Maria Pomoni,Herbert Langenberger,Marcus Schuchmann,Jérôme Dumortier,Christian A. Mueller,Patrick Chevallier,Riccardo Lencioni +19 more
TL;DR: TACE with DC Bead and doxorubicin is safe and effective in the treatment of HCC and offers a benefit to patients with more advanced disease.
Journal ArticleDOI
Targeted Disruption of the Mouse Caspase 8 Gene Ablates Cell Death Induction by the TNF Receptors, Fas/Apo1, and DR3 and Is Lethal Prenatally
Eugene Varfolomeev,Marcus Schuchmann,Victor Luria,N. Chiannilkulchai,Jacques S. Beckmann,Igor Mett,Denis V. Rebrikov,Vadim M Brodianski,Oliver Kemper,Orit Kollet,Tsvee Lapidot,Dror Soffer,Tama Sobe,Karen B. Avraham,Tanya Goncharov,Helmut Holtmann,Peter Lonai,David Wallach +17 more
TL;DR: Findings indicate that Caspase 8 plays a necessary and nonredundant role in death induction by several receptors of the TNF/NGF family and serves a vital role in embryonal development.
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Interleukin-33-Dependent Innate Lymphoid Cells Mediate Hepatic Fibrosis
Tamar Mchedlidze,Maximilian J. Waldner,Steffen Zopf,Jennifer A. Walker,Andrew L. Rankin,Marcus Schuchmann,David Voehringer,Andrew N. J. McKenzie,Markus F. Neurath,Stefan Pflanz,Stefan Wirtz +10 more
TL;DR: It is reported that hepatic expression of interleukin-33 was both required and sufficient for severe hepatic fibrosis in vivo and support the concept of modulation of IL-33 bioactivity for therapeutic purposes.
Journal ArticleDOI
Response to transarterial chemoembolization as a biological selection criterion for liver transplantation in hepatocellular carcinoma
Gerd Otto,Sascha Herber,Michael Heise,Ansgar W. Lohse,Christian Mönch,Fernando Bittinger,Maria Hoppe-Lotichius,Marcus Schuchmann,Anja Victor,Michael B. Pitton +9 more
TL;DR: Sustained response to TACE is a better selection criterion for LT than the initial assessment of tumor size or number, according to the multivariate analysis.
Journal ArticleDOI
Faldaprevir and deleobuvir for HCV genotype 1 infection.
Stefan Zeuzem,Vincent Soriano,Tarik Asselah,Jean-Pierre Bronowicki,Ansgar W. Lohse,Beat Müllhaupt,Marcus Schuchmann,Marc Bourlière,Maria Buti,Stuart K. Roberts,Edward Gane,Jerry O. Stern,Richard Vinisko,George Kukolj,John-Paul Gallivan,W. Böcher,Federico J. Mensa +16 more
TL;DR: The rate of a sustained virologic response 12 weeks after the completion of therapy was 52 to 69% among patients who received interferon-free treatment with faldaprevir in combination with deleobuvir plus ribavirin.