M
Michael Heise
Researcher at University of Mainz
Publications - 82
Citations - 2760
Michael Heise is an academic researcher from University of Mainz. The author has contributed to research in topics: Liver transplantation & Transplantation. The author has an hindex of 24, co-authored 78 publications receiving 2446 citations. Previous affiliations of Michael Heise include Charité & University of Jena.
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Journal ArticleDOI
Response to transarterial chemoembolization as a biological selection criterion for liver transplantation in hepatocellular carcinoma
Gerd Otto,Sascha Herber,Michael Heise,Ansgar W. Lohse,Christian Mönch,Fernando Bittinger,Maria Hoppe-Lotichius,Marcus Schuchmann,Anja Victor,Michael B. Pitton +9 more
TL;DR: Sustained response to TACE is a better selection criterion for LT than the initial assessment of tumor size or number, according to the multivariate analysis.
Journal ArticleDOI
Sirolimus Use in Liver Transplant Recipients With Hepatocellular Carcinoma: A Randomized, Multicenter, Open-Label Phase 3 Trial
Edward K. Geissler,Andreas A. Schnitzbauer,Andreas A. Schnitzbauer,Carl Zülke,P. Lamby,Andrea Proneth,Christophe Duvoux,Patrizia Burra,Karl-Walter Jauch,Markus Rentsch,Tom M. Ganten,Jan Schmidt,Utz Settmacher,Michael Heise,Michael Heise,Giorgio Rossi,Umberto Cillo,Norman M. Kneteman,René Adam,Bart van Hoek,Philippe Bachellier,Philippe Wolf,Lionel Rostaing,Wolf O. Bechstein,Magnus Rizell,James J. Powell,Ernest Hidalgo,J. Gugenheim,Heiner Wolters,Jens Brockmann,André Roy,Ingrid Mutzbauer,Angela Schlitt,Susanne Beckebaum,Christian Graeb,Silvio Nadalin,Umberto Valente,Victor Sanchez Turrion,Neville V. Jamieson,T. Scholz,Michele Colledan,Fred Fändrich,Thomas Becker,Gunnar Söderdahl,Olivier Chazouillères,Heikki Mäkisalo,Georges-Philippe Pageaux,Rudolf Steininger,Thomas Soliman,Koert P. de Jong,Jacques Pirenne,Raimund Margreiter,Johann Pratschke,Antonio Daniele Pinna,Johann Hauss,Stefan Schreiber,Simone I. Strasser,Jürgen Klempnauer,Roberto Troisi,Sherrie Bhoori,Jan Lerut,Itxarone Bilbao,Christian Klein,Alfred Königsrainer,Darius F. Mirza,Gerd Otto,Vincenzo Mazzaferro,Peter Neuhaus,Hans J. Schlitt +68 more
TL;DR: This trial provides the first high-level evidence base for selecting immunosuppression in LTx recipients with HCC and reveals that low-risk, rather than high- risk, patients benefited most from sirolimus; furthermore, younger recipients (age ⩽60) also benefited, as well siro Limus monotherapy patients.
Journal ArticleDOI
Venous complications after orthotopic liver transplantation
Utz Settmacher,N.C Nüssler,Matthias Glanemann,R Haase,Michael Heise,Wolf O. Bechstein,Peter Neuhaus +6 more
TL;DR: Treatment for venous complications following 1000 orthotopic liver transplantations was dependent on the signs and symptoms of the patients, and varied considerably between patients with portal vein complications and patients suffering from complications of the vena cava.
Journal ArticleDOI
A prospective randomised, open-labeled, trial comparing sirolimus-containing versus mTOR-inhibitor-free immunosuppression in patients undergoing liver transplantation for hepatocellular carcinoma
Andreas A. Schnitzbauer,Carl Zuelke,Christian Graeb,Justine Rochon,Itxarone Bilbao,Patrizia Burra,Koert P. de Jong,Christophe Duvoux,Norman M. Kneteman,René Adam,Wolf O. Bechstein,Thomas Becker,Susanne Beckebaum,Olivier Chazouillères,Umberto Cillo,Michele Colledan,Fred Fändrich,Jean Gugenheim,Johann Hauss,Michael Heise,Ernest Hidalgo,Neville V. Jamieson,Alfred Königsrainer,P. Lamby,Jan Lerut,Heikki Mäkisalo,Raimund Margreiter,Vincenzo Mazzaferro,Ingrid Mutzbauer,Gerd Otto,Georges-Philippe Pageaux,Antonio Daniele Pinna,Jacques Pirenne,Magnus Rizell,Giorgio Rossi,Lionel Rostaing,André Roy,Victor Sanchez Turrion,Jan Schmidt,Roberto Troisi,Bart van Hoek,Umberto Valente,Philippe Wolf,Heiner Wolters,Darius F. Mirza,T. Scholz,Rudolf Steininger,Gunnar Söderdahl,Simone I. Strasser,Karl-Walter Jauch,Peter Neuhaus,Hans J. Schlitt,Edward K Geissler +52 more
TL;DR: If the hypothesis is correct that mTOR inhibition can reduce HCC tumour growth while simultaneously providing immunosuppression to protect the liver allograft from rejection, patients should experience less post-transplant problems with HCC recurrence, and therefore could expect a longer and better quality of life.
Journal ArticleDOI
Radiofrequency ablation as first-line treatment in patients with early colorectal liver metastases amenable to surgery.
Gerd Otto,Christoph Düber,Maria Hoppe-Lotichius,Jochem König,Michael Heise,Michael B. Pitton +5 more
TL;DR: Despite striking differences in local tumor recurrence and shorter time to progression, survival in patients with early CRLM does not depend on the mode of primary hepatic treatment.