M
María P. Torres
Researcher at University of Nebraska Medical Center
Publications - 11
Citations - 1069
María P. Torres is an academic researcher from University of Nebraska Medical Center. The author has contributed to research in topics: Pancreatic cancer & Mucin. The author has an hindex of 11, co-authored 11 publications receiving 916 citations. Previous affiliations of María P. Torres include Eppley Institute for Research in Cancer and Allied Diseases.
Papers
More filters
Journal ArticleDOI
Detection of the potential pancreatic cancer marker MUC4 in serum using surface-enhanced Raman scattering.
Gufeng Wang,Robert J. Lipert,Maneesh Jain,Sukwinder Kaur,Subhankar Chakraboty,María P. Torres,Surinder K. Batra,Randall E. Brand,Marc D. Porter +8 more
TL;DR: Results indicate that a SERS-based immunoassay can monitor MUC4 levels in patient sera, representing a much needed first step toward assessing the potential of this protein to serve as a serum marker for the early stage diagnosis of PC.
Journal ArticleDOI
Graviola: A novel promising natural-derived drug that inhibits tumorigenicity and metastasis of pancreatic cancer cells in vitro and in vivo through altering cell metabolism
María P. Torres,Satyanarayana Rachagani,Vinee Purohit,Poomy Pandey,Suhasini Joshi,Erik D. Moore,Sonny L. Johansson,Pankaj K. Singh,Apar Kishor Ganti,Surinder K. Batra +9 more
TL;DR: Overall, the compounds that are naturally present in a Graviola extract inhibited multiple signaling pathways that regulate metabolism, cell cycle, survival, and metastatic properties in PC cells, indicating promising characteristics of the natural product against this lethal disease.
Journal ArticleDOI
Current status of mucins in the diagnosis and therapy of cancer
TL;DR: The current status of the distribution of mucins in normal and pathologic conditions and their clinical use both in cancer diagnosis and therapeutics treatments are focused on.
Journal ArticleDOI
Effects of Thymoquinone in the Expression of Mucin 4 in Pancreatic Cancer Cells: Implications for the Development of Novel Cancer Therapies
María P. Torres,Moorthy P. Ponnusamy,Subhankar Chakraborty,Lynette M. Smith,Srustidhar Das,Hwyda A. Arafat,Surinder K. Batra +6 more
TL;DR: Treatment with TQ downregulated MUC4 expression through the proteasomal pathway and induced apoptosis in pancreatic cancer cells by the activation of c-Jun NH2-terminal kinase and p38 mitogen-activated protein kinase pathways.
Journal ArticleDOI
Novel pancreatic cancer cell lines derived from genetically engineered mouse models of spontaneous pancreatic adenocarcinoma: Applications in diagnosis and therapy
María P. Torres,Satyanarayana Rachagani,Joshua J. Souchek,Kavita Mallya,Sonny L. Johansson,Surinder K. Batra,Surinder K. Batra +6 more
TL;DR: The successful establishment and characterization of three cell lines derived from two PDAC mouse models that mimic the genetic compendium of human PDAC make them valuable models with a high potential of translational relevance for examining diagnostic markers and therapeutic drugs.