M
Maria Raquel Moita
Researcher at Instituto Gulbenkian de Ciência
Publications - 2
Citations - 186
Maria Raquel Moita is an academic researcher from Instituto Gulbenkian de Ciência. The author has contributed to research in topics: Internal medicine & Transcriptome. The author has an hindex of 1, co-authored 1 publications receiving 138 citations.
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Metabolic Adaptation Establishes Disease Tolerance to Sepsis
Sebastian Weis,Ana Rita Carlos,Maria Raquel Moita,Sumnima Singh,Birte Blankenhaus,Silvia Cardoso,Rasmus Larsen,Sofia Rebelo,Sascha Schäuble,Laura del Barrio,Gilles Mithieux,Fabienne Rajas,Sandro Lindig,Michael Bauer,Miguel P. Soares +14 more
TL;DR: It is demonstrated that induction of the iron-sequestering ferritin H chain in response to polymicrobial infections is critical to establish disease tolerance to sepsis and a crosstalk between adaptive responses controlling iron and glucose metabolism is required to maintain blood glucose within a physiologic range compatible with host survival.
Journal ArticleDOI
Transcriptome and proteome profiling of activated cardiac fibroblasts supports target prioritization in cardiac fibrosis
Maria Raquel Moita,Marta Silva,Claudia Diniz,Margarida Serra,Rene Hoet,Ana Barbas,Daniel Simão +6 more
TL;DR: In this paper , the authors studied the cell state conversion from quiescent to activated cardiac fibroblasts (CF) at transcriptomic and proteomic levels, using three different cell sources: primary adult CF (aHCF), primary fetal CF (fHCF) and induced pluripotent stem cells derived CF (hiPSC-CF).