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Maria Spolidoro

Researcher at École Normale Supérieure

Publications -  5
Citations -  524

Maria Spolidoro is an academic researcher from École Normale Supérieure. The author has contributed to research in topics: Motor cortex & Sensory system. The author has an hindex of 5, co-authored 5 publications receiving 414 citations. Previous affiliations of Maria Spolidoro include French Institute of Health and Medical Research & Centre national de la recherche scientifique.

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α‐synuclein assemblies sequester neuronal α3‐Na+/K+‐ATPase and impair Na+ gradient

TL;DR: It is demonstrated that α‐syn assemblies form clusters within the plasma membrane of neurons, resulting in α3‐NKA redistribution and formation of larger nanoclusters and decreasing the efficiency of Na+ extrusion following stimulus.
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Burst-Dependent Bidirectional Plasticity in the Cerebellum Is Driven by Presynaptic NMDA Receptors

TL;DR: It is found that high-frequency bursts are necessary to trigger LTP and that this burst-dependent plasticity depends on presynaptic NMDA receptors and nitric oxide (NO) signaling and a mechanistic plasticity model based on NO and calcium signaling is developed.
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Data in support of the identification of neuronal and astrocyte proteins interacting with extracellularly applied oligomeric and fibrillar α-synuclein assemblies by mass spectrometry.

TL;DR: The data presented here support the proteomic analysis used to identify neuronal proteins that specifically interact with extracellularly applied oligomeric or fibrillar α-syn assemblies (conditions 1 and 2, respectively) (doi: 10.15252/embj.201591397).