M
Marieke L. Kuijjer
Researcher at University of Oslo
Publications - 80
Citations - 3310
Marieke L. Kuijjer is an academic researcher from University of Oslo. The author has contributed to research in topics: Osteosarcoma & Regulation of gene expression. The author has an hindex of 26, co-authored 69 publications receiving 2424 citations. Previous affiliations of Marieke L. Kuijjer include Boston University & Harvard University.
Papers
More filters
Journal ArticleDOI
Somatic mosaic IDH1 and IDH2 mutations are associated with enchondroma and spindle cell hemangioma in Ollier disease and Maffucci syndrome
Twinkal C. Pansuriya,Ronald van Eijk,Pio D'Adamo,Maayke A. J. H. van Ruler,Marieke L. Kuijjer,Jan Oosting,Anne-Marie Cleton-Jansen,Jolieke G. van Oosterwijk,Sofie L. J. Verbeke,Danielle Meijer,Tom van Wezel,Karolin Hansén Nord,Luca Sangiorgi,Berkin Toker,Bernadette Liegl-Atzwanger,Mikel San-Julian,Raf Sciot,Nisha Limaye,Lars-Gunnar Kindblom,Soeren Daugaard,Catherine Godfraind,Laurence M. Boon,Laurence M. Boon,Miikka Vikkula,Miikka Vikkula,Kyle C. Kurek,Karoly Szuhai,Pim J. French,Judith V.M.G. Bovée +28 more
TL;DR: Somatic heterozygous mutations in IDH1 or IDH2 mutations in cartilage tumors were associated with hypermethylation and downregulated expression of several genes and suggested intraneoplastic and somatic mosaicism.
Journal ArticleDOI
Tumor-Infiltrating Macrophages Are Associated with Metastasis Suppression in High-Grade Osteosarcoma: A Rationale for Treatment with Macrophage Activating Agents
Emilie P. Buddingh,Marieke L. Kuijjer,Ronald A.J. Duim,Horst Bürger,Konstantin Agelopoulos,Ola Myklebost,Massimo Serra,Fredrik Mertens,Pancras C.W. Hogendoorn,Arjan C. Lankester,Anne-Marie Cleton-Jansen +10 more
TL;DR: A biological rationale for the adjuvant treatment of high-grade osteosarcoma patients with macrophage activating agents, such as muramyl tripeptide is provided.
Journal ArticleDOI
Understanding Tissue-Specific Gene Regulation
Abhijeet R. Sonawane,Abhijeet R. Sonawane,John Platig,Maud Fagny,Cho Yi Chen,Joseph N. Paulson,Camila M. Lopes-Ramos,Dawn L. DeMeo,Dawn L. DeMeo,John Quackenbush,Kimberly Glass,Kimberly Glass,Marieke L. Kuijjer +12 more
TL;DR: It is found that network edges have higher tissue specificity than network nodes (genes) and that regulating nodes (transcription factors) are less likely to be expressed in a tissue-specific manner as compared to their targets ( Genotype-Tissue Expression).
Journal ArticleDOI
Modulation of the Osteosarcoma Expression Phenotype by MicroRNAs
Heidi M. Namløs,Leonardo A. Meza-Zepeda,Leonardo A. Meza-Zepeda,Tale Barøy,Ingrid H.G. Østensen,Stine H. Kresse,Marieke L. Kuijjer,Massimo Serra,Horst Bürger,Anne-Marie Cleton-Jansen,Ola Myklebost,Ola Myklebost +11 more
TL;DR: This study provides an integrated analysis of miRNA and mRNA in osteosarcoma, and gives new insight into the complex genetic mechanisms of osteosARcoma development and progression, as well as identifying 177 miRNAs that were differentially expressed in osteOSarcomA cell lines relative to normal bone.
Journal ArticleDOI
Sex Differences in Gene Expression and Regulatory Networks across 29 Human Tissues
Camila M. Lopes-Ramos,Cho Yi Chen,Marieke L. Kuijjer,Joseph N. Paulson,Abhijeet R. Sonawane,Maud Fagny,John Platig,Kimberly Glass,Kimberly Glass,John Quackenbush,John Quackenbush,Dawn L. DeMeo +11 more
TL;DR: This systems-based analysis identifies a repertoire of TFs that play important roles in sex-specific architecture of gene regulatory networks, and it underlines sex- specific regulatory processes in both health and disease.