M
Mario C. Deng
Researcher at University of California, Los Angeles
Publications - 343
Citations - 9577
Mario C. Deng is an academic researcher from University of California, Los Angeles. The author has contributed to research in topics: Transplantation & Heart transplantation. The author has an hindex of 47, co-authored 332 publications receiving 8574 citations. Previous affiliations of Mario C. Deng include Ronald Reagan UCLA Medical Center & University of Münster.
Papers
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Journal ArticleDOI
Noninvasive discrimination of rejection in cardiac allograft recipients using gene expression profiling
Mario C. Deng,H. J. Eisen,Mandeep R. Mehra,M. Billingham,Charles C. Marboe,Gerald J. Berry,Jon A. Kobashigawa,F. L. Johnson,Randall C. Starling,S. Murali,D. F. Pauly,H. Baron,J. G. Wohlgemuth,Robert Woodward,T. M. Klingler,Dirk Walther,P. G. Lal,Steve Rosenberg,Sharon A. Hunt +18 more
TL;DR: Gene expression testing can detect absence of moderate/severe rejection, thus avoiding biopsy in certain clinical settings, and the role of molecular testing for clinical event prediction and immunosuppression management is established.
Journal ArticleDOI
Gene-Expression Profiling for Rejection Surveillance after Cardiac Transplantation
M.X. Pham,M.X. Pham,Jeffrey J. Teuteberg,Abdallah G. Kfoury,Randall C. Starling,Mario C. Deng,Thomas P. Cappola,Andrew Kao,Allen S. Anderson,William Cotts,Gregory A. Ewald,David A. Baran,Roberta C. Bogaev,Barbara Elashoff,Helen M. Baron,J. Yee,Hannah A. Valantine +16 more
TL;DR: Among selected patients who had received a cardiac transplant more than 6 months previously and who were at a low risk for rejection, a strategy of monitoring for rejection that involved gene-expression profiling, as compared with routine biopsy was not associated with an increased risk of serious adverse outcomes and resulted in the performance of significantly fewer biopsies.
Journal ArticleDOI
Registry of the International Society for Heart and Lung Transplantation: twenty-second official adult heart transplant report--2005.
David O. Taylor,Leah B. Edwards,Mark M. Boucek,Elbert P. Trulock,Mario C. Deng,Berkeley M. Keck,Marshall I. Hertz +6 more
Journal ArticleDOI
Ex-vivo perfusion of donor hearts for human heart transplantation (PROCEED II): a prospective, open-label, multicentre, randomised non-inferiority trial
Abbas Ardehali,Fardad Esmailian,Mario C. Deng,Edward G. Soltesz,Eileen Hsich,Yoshifumi Naka,Donna M. Mancini,Margarita Camacho,Mark J. Zucker,Pascal Leprince,Robert F. Padera,Jon A. Kobashigawa +11 more
TL;DR: Heart transplantation using donor hearts adequately preserved with the Organ Care System or with standard cold storage yield similar short-term clinical outcomes and the metabolic assessment capability of the Organ care System needs further study.
Journal ArticleDOI
Mechanical Circulatory Support device database of the International Society for Heart and Lung Transplantation: first annual report--2003.
TL;DR: The Scientific Council on Mechanical Circulatory Support of the International Society for Heart and Lung Transplantation has established an international database to generate critical data to advance knowledge about the effectiveness of mechanical circulatory support device therapy for one of the most difficult and costly contemporary medical problems, the malignant syndrome of advanced heart failure.