Mark A. Guelta

TL;DR: For the first time, a nerve agent detoxifying enzyme, organophosphorus acid anhydrolase (OPAA), has been successfully encapsulated into a water-stable zirconium metal-organic framework (MOF), which features a hierarchical mesoporous channel structure and exhibits a 12 wt % loading capacity.

TL;DR: The synthesis and characterization of a water-stable zirconium metal-organic framework (MOF), NU-1003, featuring the largest mesoporous aperture known for a zIRconium MOF, is reported, highlighting a method for rapid and highly efficient hydrolysis of nerve agents using nanosized enzyme carriers.

TL;DR: The U.S. Army has custody of chemical weapons (CW) containing nerve and blister (vesicant) agents located in eight sites in the continental United States and at Johnston Island, a small island in the Pacific Ocean as discussed by the authors.

TL;DR: In this article, the U.S. Army is required to destroy its stockpile of chemical warfare agents (30,000 tons) by April 2007, and public and political opposition to incineration lead to evaluation of several alternative technologies, including biodegradation 1.

TL;DR: In this article, a non-wild-type organophosphorus acid anhydrolase enzyme with two site mutations, method of production, and method of use to more effectively degrade toxic organophorus compounds and, in particular, toxic chemical GD (3,3-Dimethylbutan-2-ylmethylphosphonofluoridate), was proposed.