Journal ArticleDOI
Encapsulation of a Nerve Agent Detoxifying Enzyme by a Mesoporous Zirconium Metal-Organic Framework Engenders Thermal and Long-Term Stability.
Peng Li,Su-Young Moon,Mark A. Guelta,Steven P. Harvey,Joseph T. Hupp,Omar K. Farha,Omar K. Farha +6 more
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TLDR
For the first time, a nerve agent detoxifying enzyme, organophosphorus acid anhydrolase (OPAA), has been successfully encapsulated into a water-stable zirconium metal-organic framework (MOF), which features a hierarchical mesoporous channel structure and exhibits a 12 wt % loading capacity.Abstract:
Immobilized enzymes typically have greater thermal and operational stability than their soluble form. Here we report that for the first time, a nerve agent detoxifying enzyme, organophosphorus acid anhydrolase (OPAA), has been successfully encapsulated into a water-stable zirconium metal–organic framework (MOF). This MOF features a hierarchical mesoporous channel structure and exhibits a 12 wt % loading capacity of OPAA. The thermal and long-term stabilities of OPAA are both significantly enhanced after immobilization.read more
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Nanozymes: Classification, Catalytic Mechanisms, Activity Regulation, and Applications
TL;DR: This review systematically introduces the classification, catalytic mechanism, activity regulation as well as recent research progress of nanozymes in the field of biosensing, environmental protection, and disease treatments, etc. in the past years.
Journal ArticleDOI
Enzyme–MOF (metal–organic framework) composites
Xizhen Lian,Yu Fang,Elizabeth A. Joseph,Qi Wang,Jialuo Li,Sayan Banerjee,Christina T. Lollar,Xuan Wang,Hong-Cai Zhou +8 more
TL;DR: This review summarizes recent developments of MOF-enzyme composites with special emphasis on preparative techniques and the synergistic effects of enzymes and MOFs.
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Hybridization of MOFs and polymers
TL;DR: This review article focuses on the methodology for hybridization of MOFs and polymers, as well as the intriguing functions of hybrid materials.
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Controllable design of tunable nanostructures inside metal-organic frameworks.
TL;DR: This tutorial review article summarized the state-of-the-art development of MOFs containing encapsulated tunable nanoentities, with special emphasis on the preparation and synergistic properties of these composites.
Journal ArticleDOI
Metal-Organic Frameworks at the Biointerface: Synthetic Strategies and Applications
TL;DR: It is demonstrated that a class of porous materials termed metal-organic frameworks (MOFs) can spontaneously form on protein-based hydrogels via a process analogous to natural matrix-mediated biomineralization, and that cells encapsulated within a crystalline MOF shell remain viable after exposure to a medium containing lytic enzymes.
References
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Journal ArticleDOI
The Chemistry and Applications of Metal-Organic Frameworks
Hiroyasu Furukawa,Hiroyasu Furukawa,Kyle E. Cordova,Kyle E. Cordova,Michael O'Keeffe,Michael O'Keeffe,Omar M. Yaghi,Omar M. Yaghi,Omar M. Yaghi +8 more
TL;DR: Metal-organic frameworks are porous materials that have potential for applications such as gas storage and separation, as well as catalysis, and methods are being developed for making nanocrystals and supercrystals of MOFs for their incorporation into devices.
Journal ArticleDOI
Reticular Chemistry: Occurrence and Taxonomy of Nets and Grammar for the Design of Frameworks
TL;DR: The structures of all 1127 three-periodic extended metal-organic frameworks reported in the Cambridge Structure Database have been analyzed, and their underlying topology has been determined, leading to a system of classification "taxonomy" for interpreting and rationalizing known MOF structures.
Journal ArticleDOI
Water stability and adsorption in metal-organic frameworks.
Journal ArticleDOI
Water Adsorption in Porous Metal–Organic Frameworks and Related Materials
Hiroyasu Furukawa,Felipe Gándara,Yue-Biao Zhang,Juncong Jiang,Wendy L. Queen,Matthew R. Hudson,Omar M. Yaghi +6 more
TL;DR: MOF-801-P and MOF-841 are the highest performers based on the three criteria stated above; they are water stable, do not lose capacity after five adsorption/desorption cycles, and are easily regenerated at room temperature.
Journal ArticleDOI
Large-Pore Apertures in a Series of Metal-Organic Frameworks
Hexiang Deng,Sergio Grunder,Kyle E. Cordova,Cory Valente,Hiroyasu Furukawa,Mohamad Hmadeh,Felipe Gándara,Adam C. Whalley,Zheng Liu,Shunsuke Asahina,Hiroyoshi Kazumori,Michael O'Keeffe,Osamu Terasaki,Osamu Terasaki,J. Fraser Stoddart,J. Fraser Stoddart,Omar M. Yaghi,Omar M. Yaghi +17 more
TL;DR: A strategy to expand the pore aperture of metal-organic frameworks (MOFs) into a previously unattained size regime (>32 angstroms) is reported, as evidenced by their permanent porosity and high thermal stability (up to 300°C).