M
Marta Martín-Fernández
Researcher at University of Valladolid
Publications - 11
Citations - 587
Marta Martín-Fernández is an academic researcher from University of Valladolid. The author has contributed to research in topics: Sepsis & Internal medicine. The author has an hindex of 7, co-authored 11 publications receiving 214 citations.
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Journal ArticleDOI
Current gaps in sepsis immunology: new opportunities for translational research.
Ignacio Rubio,Marcin F. Osuchowski,Manu Shankar-Hari,Manu Shankar-Hari,Tomasz Skirecki,Martin Sebastian Winkler,Gunnar Lachmann,Paul La Rosée,Guillaume Monneret,Fabienne Venet,Michael Bauer,Frank M. Brunkhorst,Matthijs Kox,Jean-Marc Cavaillon,Florian Uhle,Markus A. Weigand,Stefanie B. Flohé,W. Joost Wiersinga,Marta Martín-Fernández,Raquel Almansa,Raquel Almansa,Ignacio Martin-Loeches,Antoni Torres,Antoni Torres,Evangelos J. Giamarellos-Bourboulis,Massimo Girardis,Andrea Cossarizza,Mihai G. Netea,Mihai G. Netea,Mihai G. Netea,Tom van der Poll,André Scherag,Christian Meisel,Joerg C. Schefold,Jesus F. Bermejo-Martin,Jesus F. Bermejo-Martin +35 more
TL;DR: The role of key immune cells, the cause of lymphopenia, organ-specific immunology, the dynamics of sepsis-associated immunological alterations, the role of the microbiome, the standardisation of immunological tests, the development of better animal models, and the opportunities offered by immunotherapy are discussed.
Journal ArticleDOI
Viral RNA load in plasma is associated with critical illness and a dysregulated host response in COVID-19.
Jesus F. Bermejo-Martin,Jesus F. Bermejo-Martin,Milagros González-Rivera,Milagros González-Rivera,Raquel Almansa,Raquel Almansa,Dariela Micheloud,Ana P. Tedim,Marta Domínguez-Gil,Salvador Resino,Marta Martín-Fernández,Pablo Ryan Murua,Felipe Pérez-García,Luis Tamayo,Raul Lopez-Izquierdo,Elena Bustamante,Cesar Aldecoa,José Manuel Gómez,Jesús Rico-Feijoo,Antonio Orduña,Raúl Méndez,Isabel Fernandez Natal,Gregoria Megias,Montserrat Gonzalez-Estecha,Montserrat Gonzalez-Estecha,Demetrio Carriedo,Cristina Doncel,Cristina Doncel,Noelia Jorge,Noelia Jorge,Alicia Ortega,Alicia Ortega,Amanda de la Fuente,Amanda de la Fuente,Félix del Campo,Jose Antonio Fernandez-Ratero,Wysali Trapiello,Paula González-Jiménez,Guadalupe Ruiz,Alyson A. Kelvin,Alyson A. Kelvin,Ali Toloue Ostadgavahi,Ali Toloue Ostadgavahi,Ruth Oneizat,Luz Maria Ruiz,Iria Miguens,Esther Gargallo,Ioana Muñoz,Sara Pelegrin,Silvia Martín,P. Olivares,Jamil Antonio Cedeno,Tomás Ruiz Albi,Carolina Puertas,Jose Ángel Berezo,Gloria Renedo,Ruben Herran,Juan Bustamante-Munguira,Pedro Enriquez,Ramón Cicuendez,Jesús Blanco,Jesica Abadia,Julia Gómez Barquero,Nuria Mamolar,Natalia Blanca-López,Luis Jorge Valdivia,Belen Fernandez Caso,Maria Angeles Mantecon,Anna Motos,Anna Motos,Laia Fernández-Barat,Laia Fernández-Barat,Ricard Ferrer,Ferran Barbé,Antoni Torres,Antoni Torres,Rosario Menéndez,Rosario Menéndez,José María Eiros,David J. Kelvin,David J. Kelvin +80 more
TL;DR: Viral RNA load in plasma correlates with key signatures of dysregulated host responses, suggesting a major role of uncontrolled viral replication in the pathogenesis of this disease.
Posted ContentDOI
SARS-CoV-2-RNA viremia is associated to hypercytokinemia and critical illness in COVID-19
Jesus F. Bermejo-Martin,Milagros González-Rivera,Milagros González-Rivera,Raquel Almansa,Dariela Micheloud,Ana P. Tedim,Marta Domínguez-Gil,Salvador Resino,Marta Martín-Fernández,Pablo Ryan Murua,Felipe Pérez-García,Luis Tamayo,Raul Lopez-Izquierdo,Elena Bustamante,Cesar Aldecoa,José Manuel Gómez,Jesús Rico-Feijoo,Antonio Orduña,Raúl Méndez,Isabel Fernandez Natal,Gregoria Megias,Montserrat Gonzalez-Estecha,Montserrat Gonzalez-Estecha,Demetrio Carriedo,Cristina Doncel,Noelia Jorge,Alicia Ortega,Amanda de la Fuente,Félix del Campo,Jose Antonio Fernandez-Ratero,Wysali Trapiello,Paula González-Jiménez,Guadalupe Ruiz,Alyson A. Kelvin,Alyson A. Kelvin,Ali Toloue Ostadgavahi,Ali Toloue Ostadgavahi,Ruth Oneizat,Luz Maria Ruiz,Iria Miguens,Esther Gargallo,Iona Munoz,Sara Pelegrin,Silvia Martín,Pablo Garcia-Olivares,Jamil Antonio Cedeno,Tomas Ruiz-Albi,Carolina Puertas,Jose Ángel Berezo,Gloria Renedo,Ruben Herran,Juan Bustamante-Munguira,Pedro Enriquez,Ramón Cicuendez,Jesús Blanco,Jessica Abadia,Julia Gomez-Barquero,Nuria Mamolar,Natalia Blanca-López,Luis Jorge Valdivia,Belen Fernandez Caso,Maria Angeles Mantecon,Anna Motos,Anna Motos,Laia Fernández-Barat,Laia Fernández-Barat,Ricard Ferrer,Ferran Barbé,Antoni Torres,Antoni Torres,Rosario Menéndez,Rosario Menéndez,José María Eiros,David J. Kelvin,David J. Kelvin +74 more
TL;DR: Viral RNA load in plasma correlates with key signatures of dysregulated host responses, suggesting a major role of uncontrolled viral replication in the pathogenesis of this disease.
Journal ArticleDOI
Quantification of Immune Dysregulation by Next-generation Polymerase Chain Reaction to Improve Sepsis Diagnosis in Surgical Patients.
Raquel Almansa,Alicia Ortega,Ana Ávila-Alonso,María Heredia-Rodríguez,Silvia Martín,Diana Benavides,Marta Martín-Fernández,Lucia Rico,Cesar Aldecoa,Jesús Rico,Iñigo López de Cenarruzabeitia,Juan Beltran de Heredia,Esther Gómez-Sánchez,Marta Aragón,C. Andres,Dolores Calvo,David Andaluz-Ojeda,Pilar Liu,Francisco Blanco-Antona,Lydia Blanco,José Ignacio Gómez-Herreras,Eduardo Tamayo,Jesus F. Bermejo-Martin +22 more
TL;DR: Quantifying the transcriptomic ratios MMP8/HLA-DRA, LCN2/ HLA- DRA by ddPCR is a promising approach to improve sepsis diagnosis in surgical patients.
Journal ArticleDOI
Lipid peroxidation as a hallmark of severity in COVID-19 patients.
Marta Martín-Fernández,Rocío Aller,María Heredia-Rodríguez,Esther Gómez-Sánchez,Pedro Martínez-Paz,Hugo Gonzalo-Benito,Laura Sánchez-de Prada,Óscar Gorgojo,Irene Carnicero-Frutos,Eduardo Tamayo,Álvaro Tamayo-Velasco +10 more
TL;DR: In this article, a multivariable regression analysis was performed to evaluate the relationship between lipid peroxidation and 28-day intubation/death risk in COVID-19 patients.